Literature DB >> 16228225

Recurrent high-grade leiomyosarcoma with heterologous osteosarcomatous differentiation.

Florian Grabellus1, Sien-Yi Sheu, Boris Schmidt, Michael Flasshove, Cornelius Kuhnen, Steffen Ruchholtz, Georg Taeger, Kurt Werner Schmid.   

Abstract

Leiomyosarcomas (LM) of the soft tissue comprise approximately 5-10% of all soft tissue sarcomas. Besides the classic LM, several distinctly uncommon features of the cellular and growth patterns of LM have been described. The term "dedifferentiated LM" has rarely been used in the literature to describe soft tissue LM containing areas of undifferentiated, pleomorphic appearance or detectable heterologous differentiation. We report on a case of high-grade LM with almost entire transition to an osteosarcoma, which was classified as recurrent high-grade LM with heterologous osteosarcomatous differentiation. The identification of areas with osteosarcomatous dedifferentiation in soft tissue sarcomas can be of clinical importance because of a possible change in oncologic treatment strategies.

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Year:  2005        PMID： 16228225     DOI： 10.1007/s00428-005-0094-0

Source DB:  PubMed          Journal:  Virchows Arch        ISSN： 0945-6317            Impact factor:   4.064


  20 in total

1.  Extraskeletal osteosarcomas: a clinicopathologic study of 25 cases.

Authors:  M Lidang Jensen; B Schumacher; O Myhre Jensen; O Steen Nielsen; J Keller
Journal:  Am J Surg Pathol       Date:  1998-05       Impact factor: 6.394

2.  Malignant mesenchymoma. Clinicopathologic analysis of a series with evidence of low-grade behaviour.

Authors:  P L Newman; C D Fletcher
Journal:  Am J Surg Pathol       Date:  1991-07       Impact factor: 6.394

3.  Rhabdomyoblastic differentiation in a leiomyosarcoma of the retroperitoneum.

Authors:  F Roncaroli; V Eusebi
Journal:  Hum Pathol       Date:  1996-03       Impact factor: 3.466

4.  Extraosseous osteosarcoma: response to treatment and long-term outcome.

Authors:  Syed A Ahmad; Shreyaskumar R Patel; Matthew T Ballo; Treneth P Baker; Alan W Yasko; Xuemei Wang; Barry W Feig; Kelly K Hunt; Patrick P Lin; Kristen L Weber; Lei L Chen; Gunar K Zagars; Raphael E Pollock; Robert S Benjamin; Peter W T Pisters
Journal:  J Clin Oncol       Date:  2002-01-15       Impact factor: 44.544

5.  Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation.

Authors:  W H Henricks; Y C Chu; J R Goldblum; S W Weiss
Journal:  Am J Surg Pathol       Date:  1997-03       Impact factor: 6.394

6.  Malignant mesenchymoma arising from a uterine leiomyoma in the menopause.

Authors:  Cynthia C Y Kew; Thomas C Putti; Khalil Razvi
Journal:  Gynecol Oncol       Date:  2004-12       Impact factor: 5.482

7.  Extraskeletal osteosarcoma has a favourable prognosis when treated like conventional osteosarcoma.

Authors:  Sing Yu Goldstein-Jackson; Georg Gosheger; Günter Delling; Wolfgang E Berdel; G Ulrich Exner; Gernot Jundt; Jan-Nicolas Machatschek; Andreas Zoubek; Heribert Jürgens; Stefan S Bielack
Journal:  J Cancer Res Clin Oncol       Date:  2005-05-26       Impact factor: 4.553

Review 8.  [The histological features of local recurrences of soft tissue sarcomas].

Authors:  C D Fletcher
Journal:  Pathologe       Date:  1994-08       Impact factor: 1.011

9.  Malignant mesenchymoma.

Authors:  M S Brady; G Perino; G Tallini; P Russo; J M Woodruff
Journal:  Cancer       Date:  1996-02-01       Impact factor: 6.860

10.  Leiomyosarcoma with prominent osteoclast-like giant cells. Analysis of eight cases closely mimicking the so-called giant cell variant of malignant fibrous histiocytoma.

Authors:  T Mentzel; E Calonje; C D Fletcher
Journal:  Am J Surg Pathol       Date:  1994-03       Impact factor: 6.394
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  8 in total

1.  Chondrosarcomatous differentiation of a metastatic leiomyosarcoma of the uterus.

Authors:  Ivan Damjanov; Fang Fan
Journal:  Virchows Arch       Date:  2006-08-16       Impact factor: 4.064

2.  Primary intravascular myxoid leiomyosarcoma of the femoral vein presenting clinically as deep vein thrombosis: a case report.

Authors:  Manish Mani Subramaniam; Miguel Martinez-Rodriguez; Samuel Navarro; Jorge Guijarro Rosaleny; Antonio Liombart Bosch
Journal:  Virchows Arch       Date:  2007-02       Impact factor: 4.064

3.  Dedifferentiated Leiomyosarcoma of the Auricle with Heterologous Osteosarcoma Component: Case Report and Literature Review.

Authors:  Andrea Dekanić; Nives Jonjić; Anita Savić Vuković
Journal:  Case Rep Otolaryngol       Date:  2022-05-31

4.  Molecular Analysis of a Recurrent Sarcoma Identifies a Mutation in FAF1.

Authors:  Georg F Weber
Journal:  Sarcoma       Date:  2015-03-10

5.  A case of hepatic leiomyosarcoma with osteosarcomatous differentiation (malignant mesenchymoma) in a dog.

Authors:  Yuichi Takai; Tomoya Sano; Takeshi Watanabe
Journal:  J Toxicol Pathol       Date:  2019-11-08       Impact factor: 1.628

6.  High grade sarcoma with chondrosarcomatous differentiation in primary uterine leiomyosarcoma; A rare case and review of literature.

Authors:  Qandeel Sadiq; Farhan Khan
Journal:  Gynecol Oncol Rep       Date:  2021-12-11

7.  Primary leiomyosarcoma of the atrium with heterologous differentiation.

Authors:  Shaesta Zaidi; Sufia Husain; Dona Barakah
Journal:  Ann Saudi Med       Date:  2017 Sep-Oct       Impact factor: 1.526

8.  Dedifferentiated soft tissue leiomyosarcoma with heterologous osteosarcoma component: case report and review of the literature.

Authors:  Raffaele Gaeta; Davide Matera; Francesco Muratori; Giuliana Roselli; Giacomo Baldi; Domenico Andrea Campanacci; Alessandro Franchi
Journal:  Clin Sarcoma Res       Date:  2020-04-05
  8 in total

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