PURPOSE: To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy. DESIGN: Observational cases report. METHODS: Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3. RESULTS: Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening. CONCLUSIONS: In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a foveolar cystoid space different from macular edema.
PURPOSE: To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifenretinopathy. DESIGN: Observational cases report. METHODS: Two patients with tamoxifenretinopathy were imaged with fluorescein angiography and OCT 3. RESULTS:Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening. CONCLUSIONS: In both cases, OCT findings are not consistent with previous descriptions of tamoxifenretinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifenmaculopathy may include a foveolar cystoid space different from macular edema.
Authors: Joseph A Majdi; Haohua Qian; Yichao Li; Robert J Langsner; Katherine I Shea; Anant Agrawal; Daniel X Hammer; Joseph P Hanig; Ethan D Cohen Journal: Invest Ophthalmol Vis Sci Date: 2014-12-18 Impact factor: 4.799
Authors: Peter Charbel Issa; Mark C Gillies; Emily Y Chew; Alan C Bird; Tjebo F C Heeren; Tunde Peto; Frank G Holz; Hendrik P N Scholl Journal: Prog Retin Eye Res Date: 2012-12-03 Impact factor: 21.198