Literature DB >> 16223068

A structured approach to medical management: a psychosocial intervention to support pharmacotherapy in the treatment of alcohol dependence.

Helen M Pettinati1, Roger D Weiss, William Dundon, William R Miller, Dennis Donovan, Denise B Ernst, Bruce J Rounsaville.   

Abstract

OBJECTIVE: Given the national trend toward integrating substance abuse treatment into medical practice, experts in the field of alcoholism designed a psychosocial, medically based intervention to be used with pharmacotherapy in the COMBINE multisite national study, supported by the National Institute on Alcohol Abuse and Alcoholism. A main purpose of the COMBINE Study is to investigate optimal treatment for patients with alcohol dependence by combining pharmacotherapy and psychosocial interventions.
METHOD: The medically based intervention, called Medical Management (MM), was specifically constructed to be implemented by medically trained practitioners in nonspecialty settings. Each visit includes evaluations of medication safety and adherence, monitoring of alcohol use and direct advice to the patient for achieving full recovery.
RESULTS: There are several themes implicit in MM. Patient education about the disorder and about the treatment being provided are both essential. The clinician also educates the patient about how he or she has been affected by alcohol dependence. Information is given on how to take the medication(s) as prescribed, what the patient should expect from the medication(s) and what kinds of events the clinician will need to know about during treatment. Finally, the clinician and patient discuss strategies for ensuring medication safety and adherence to the prescribed regimen.
CONCLUSIONS: MM was easily implemented in the COMBINE Study with the aid of the MM Treatment Manual.

Entities:  

Mesh:

Year:  2005        PMID: 16223068     DOI: 10.15288/jsas.2005.s15.170

Source DB:  PubMed          Journal:  J Stud Alcohol Suppl        ISSN: 0363-468X


  44 in total

1.  The COMBINE Study-: An Overview of the Largest Pharmacotherapy Study to Date for Treating Alcohol Dependence.

Authors:  Helen M Pettinati; Raymond F Anton; Mark L Willenbring
Journal:  Psychiatry (Edgmont)       Date:  2006-10

2.  Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status.

Authors:  Joseph P Schacht; Patrick K Randall; Patricia K Latham; Konstantin E Voronin; Sarah W Book; Hugh Myrick; Raymond F Anton
Journal:  Neuropsychopharmacology       Date:  2017-04-14       Impact factor: 7.853

Review 3.  Update in addiction medicine for the generalist.

Authors:  Adam J Gordon; Lynn E Sullivan; Daniel P Alford; Julia H Arnsten; Marc N Gourevitch; Stefan G Kertesz; Hillary V Kunins; Joseph O Merrill; Jeffrey H Samet; David A Fiellin
Journal:  J Gen Intern Med       Date:  2007-05-10       Impact factor: 5.128

4.  Barriers to and Facilitators of Alcohol Use Disorder Pharmacotherapy in Primary Care: A Qualitative Study in Five VA Clinics.

Authors:  Emily C Williams; Carol E Achtmeyer; Jessica P Young; Douglas Berger; Geoffrey Curran; Katharine A Bradley; Julie Richards; Michael B Siegel; Evette J Ludman; Gwen T Lapham; Mark Forehand; Alex H S Harris
Journal:  J Gen Intern Med       Date:  2017-10-30       Impact factor: 5.128

5.  Randomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes.

Authors:  Brian D Kiluk; Charla Nich; Matthew B Buck; Kathleen A Devore; Tami L Frankforter; Donna M LaPaglia; Srinivas B Muvvala; Kathleen M Carroll
Journal:  Am J Psychiatry       Date:  2018-05-24       Impact factor: 18.112

6.  Combining motivational interviewing with compliance enhancement therapy (MI-CET): development and preliminary evaluation of a new, manual-guided psychosocial adjunct to alcohol-dependence pharmacotherapy.

Authors:  Jaimee L Heffner; Giao Q Tran; Candace S Johnson; Suzan Winders Barrett; Thomas J Blom; Rachel D Thompson; Robert M Anthenelli
Journal:  J Stud Alcohol Drugs       Date:  2010-01       Impact factor: 2.582

7.  Social recovery model: an 8-year investigation of adolescent 12-step group involvement following inpatient treatment.

Authors:  John F Kelly; Sandra A Brown; Ana Abrantes; Christopher W Kahler; Mark Myers
Journal:  Alcohol Clin Exp Res       Date:  2008-06-28       Impact factor: 3.455

8.  An exploratory evaluation of Take Control: A novel computer-delivered behavioral platform for placebo-controlled pharmacotherapy trials for alcohol use disorder.

Authors:  Eric G Devine; Megan L Ryan; Daniel E Falk; Joanne B Fertig; Raye Z Litten
Journal:  Contemp Clin Trials       Date:  2016-08-10       Impact factor: 2.226

9.  Topiramate treatment of alcohol use disorder in veterans with posttraumatic stress disorder: a randomized controlled pilot trial.

Authors:  Steven L Batki; David L Pennington; Brooke Lasher; Thomas C Neylan; Thomas Metzler; Angela Waldrop; Kevin Delucchi; Ellen Herbst
Journal:  Alcohol Clin Exp Res       Date:  2014-08-04       Impact factor: 3.455

10.  Effects of alcoholism typology on response to naltrexone in the COMBINE study.

Authors:  Michael P Bogenschutz; J Scott Tonigan; Helen M Pettinati
Journal:  Alcohol Clin Exp Res       Date:  2008-09-30       Impact factor: 3.455

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