Literature DB >> 16222560

Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.

Nadezhda V Kovalevskaya1, Yegor D Smurnyy, Vladimir I Polshakov, Berry Birdsall, Alan F Bradbury, Tom Frenkiel, James Feeney.   

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Year:  2005        PMID： 16222560     DOI： 10.1007/s10858-005-1475-z

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


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  18 in total

1.  The program XEASY for computer-supported NMR spectral analysis of biological macromolecules.

Authors:  C Bartels; T H Xia; M Billeter; P Güntert; K Wüthrich
Journal:  J Biomol NMR       Date:  1995-07       Impact factor: 2.835

2.  Characterization of rates of ring-flipping in trimethoprim in its ternary complexes with Lactobacillus casei dihydrofolate reductase and coenzyme analogues.

Authors:  V I Polshakov; B Birdsall; J Feeney
Journal:  Biochemistry       Date:  1999-11-30       Impact factor: 3.162

3.  Protein backbone angle restraints from searching a database for chemical shift and sequence homology.

Authors:  G Cornilescu; F Delaglio; A Bax
Journal:  J Biomol NMR       Date:  1999-03       Impact factor: 2.835

4.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

5.  The charge state of trimethoprim bound to Lactobacillus casei dihydrofolate reductase.

Authors:  G C Roberts; J Feeney; A S Burgen; S Daluge
Journal:  FEBS Lett       Date:  1981-08-17       Impact factor: 4.124

6.  Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate.

Authors:  J F Davies; T J Delcamp; N J Prendergast; V A Ashford; J H Freisheim; J Kraut
Journal:  Biochemistry       Date:  1990-10-09       Impact factor: 3.162

7.  Expression and site-directed mutagenesis of human dihydrofolate reductase.

Authors:  N J Prendergast; T J Delcamp; P L Smith; J H Freisheim
Journal:  Biochemistry       Date:  1988-05-17       Impact factor: 3.162

Review 8.  Basis of selectivity of antibacterial diaminopyrimidines.

Authors:  D P Baccanari; L F Kuyper
Journal:  J Chemother       Date:  1993-12       Impact factor: 1.714

9.  Sequence-specific 1H and 15N resonance assignments for human dihydrofolate reductase in solution.

Authors:  B J Stockman; N R Nirmala; G Wagner; T J Delcamp; M T DeYarman; J H Freisheim
Journal:  Biochemistry       Date:  1992-01-14       Impact factor: 3.162

10.  NMR studies of differences in the conformations and dynamics of ligand complexes formed with mutant dihydrofolate reductases.

Authors:  B Birdsall; J Andrews; G Ostler; S J Tendler; J Feeney; G C Roberts; R W Davies; H T Cheung
Journal:  Biochemistry       Date:  1989-02-07       Impact factor: 3.162
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  9 in total

1.  Coarse-grain simulations on NMR conformational ensembles highlight functional residues in proteins.

Authors:  Sophie Sacquin-Mora
Journal:  J R Soc Interface       Date:  2019-07-10       Impact factor: 4.118

Review 2.  Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.

Authors:  Melanie Goldstein; Nina M Goodey
Journal:  Methods Mol Biol       Date:  2021

3.  Interpretable correlation descriptors for quantitative structure-activity relationships.

Authors:  Benson M Spowage; Craig L Bruce; Jonathan D Hirst
Journal:  J Cheminform       Date:  2009-12-24       Impact factor: 5.514

4.  In pursuit of virtual lead optimization: pruning ensembles of receptor structures for increased efficiency and accuracy during docking.

Authors:  Erin S D Bolstad; Amy C Anderson
Journal:  Proteins       Date:  2009-04

5.  In pursuit of virtual lead optimization: the role of the receptor structure and ensembles in accurate docking.

Authors:  Erin S D Bolstad; Amy C Anderson
Journal:  Proteins       Date:  2008-11-15

6.  The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors.

Authors:  Jennifer M Beierlein; Lalit Deshmukh; Kathleen M Frey; Olga Vinogradova; Amy C Anderson
Journal:  Biochemistry       Date:  2009-05-19       Impact factor: 3.162

7.  Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.

Authors:  David B Bolstad; Erin S D Bolstad; Kathleen M Frey; Dennis L Wright; Amy C Anderson
Journal:  J Med Chem       Date:  2008-10-04       Impact factor: 7.446

8.  Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.

Authors:  Kathleen M Frey; Jieying Liu; Michael N Lombardo; David B Bolstad; Dennis L Wright; Amy C Anderson
Journal:  J Mol Biol       Date:  2009-02-26       Impact factor: 5.469

9.  NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions.

Authors:  James Feeney; Berry Birdsall; Nadezhda V Kovalevskaya; Yegor D Smurnyy; Emna M Navarro Peran; Vladimir I Polshakov
Journal:  Biochemistry       Date:  2011-04-14       Impact factor: 3.162
  9 in total

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