Literature DB >> 16222205

Does pregnancy affect otosclerosis?

William H Lippy1, Leonard P Berenholz, Arnold G Schuring, John M Burkey.   

Abstract

OBJECTIVE: To evaluate the effect of pregnancy on the hearing of women with otosclerosis. STUDY
DESIGN: A retrospective study of women who had undergone stapedectomy. The women were equally divided into two groups: one group with children and a control group without children. Air and bone conduction, as well as discrimination, were measured before and after stapedectomy in both groups. PATIENTS: Ninety-four women (47 with children and 47 without) were evaluated. Because many of the women had bilateral otosclerosis, the total number of ears studied was 128.
RESULTS: Mean pure tone air and bone conduction thresholds were not worse in women with children versus those women without children. In fact, mean pre- and postoperative pure tone air and bone conduction thresholds from 500 Hz through 4,000 Hz in women with children were slightly but significantly better than women without children. There was no difference in discrimination scores between groups. Within the group with children, no significant correlation was found between number of children and hearing loss. Also, no correlation was found between breastfeeding and the amount of hearing loss.
CONCLUSION: We found no adverse effect on hearing in otosclerotic women who had children compared with women without children. Even with increasing numbers of pregnancies, no deleterious impact was noted. Air conduction, bone conduction, and discrimination were not worse in women with children versus childless women. No significant correlation was found between the number of children and hearing loss, and neither did breastfeeding affect the amount of hearing loss.

Entities:  

Mesh:

Year:  2005        PMID: 16222205     DOI: 10.1097/01.MLG.0000187573.99335.85

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  6 in total

1.  Effects of Pregnancy on Otosclerosis.

Authors:  Z Jason Qian; Jennifer C Alyono
Journal:  Otolaryngol Head Neck Surg       Date:  2020-02-25       Impact factor: 3.497

Review 2.  An overview of the etiology of otosclerosis.

Authors:  Konstantinos Markou; John Goudakos
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-08-13       Impact factor: 2.503

3.  Rare variants in BMP2 and BMP4 found in otosclerosis patients reduce Smad signaling.

Authors:  Megan Ealy; Nicole C Meyer; Johnny Cruz Corchado; Isabelle Schrauwen; Andreas Bress; Markus Pfister; Guy Van Camp; Richard J H Smith
Journal:  Otol Neurotol       Date:  2014-03       Impact factor: 2.311

4.  The Epidemiology of Otosclerosis in a British Cohort.

Authors:  Michael Crompton; Barbara A Cadge; Joanna L Ziff; Andrew J Mowat; Robert Nash; Jeremy A Lavy; Harry R F Powell; Christopher P Aldren; Shakeel R Saeed; Sally J Dawson
Journal:  Otol Neurotol       Date:  2019-01       Impact factor: 2.311

5.  Unexpected Motherhood-Triggered Hearing Loss in the Two-Pore Channel (TPC) Mutant Mouse.

Authors:  Juliette Royer; José-Manuel Cancela; Jean-Marc Edeline
Journal:  Biomedicines       Date:  2022-07-15

6.  Pregnancy, Estrogen Exposure, and the Development of Otosclerosis: A Case-Control Study of 1196 Women.

Authors:  Robert J Macielak; John P Marinelli; Douglas J Totten; Christine M Lohse; Brandon R Grossardt; Matthew L Carlson
Journal:  Otolaryngol Head Neck Surg       Date:  2020-10-27       Impact factor: 5.591

  6 in total

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