| Literature DB >> 1622186 |
M Watanabe1, E Inoue, K Katsu, S Iyobe, S Mitsuhashi.
Abstract
E1040 showed the most potent activity (MIC for 90% of strains, 6.25 micrograms/ml) among beta-lactams tested against 70 strains of imipenem-resistant Pseudomonas aeruginosa. Two strains showed high-level resistance to E1040; one strain produced a type II oxyiminocephalosporin-hydrolyzing beta-lactamase (group 3), and the other produced an enzyme similar to a type II penicillinase (OXA-1). Both beta-lactamases contributed to resistance to E1040.Entities:
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Year: 1992 PMID: 1622186 PMCID: PMC190582 DOI: 10.1128/AAC.36.3.684
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191