| Literature DB >> 16219788 |
Kosuke M Teshima1, Molly Przeworski.
Abstract
Most models of positive directional selection assume codominance of the beneficial allele. We examine the importance of this assumption by implementing a coalescent model of positive directional selection with arbitrary dominance. We find that, for a given mean fixation time, a beneficial allele has a much weaker effect on diversity at linked neutral sites when the allele is recessive.Mesh:
Year: 2005 PMID: 16219788 PMCID: PMC1456198 DOI: 10.1534/genetics.105.044065
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562