| Literature DB >> 16213208 |
Richard Daneman1, Ben A Barres.
Abstract
Despite the importance of the blood-brain barrier (BBB), little is known about the molecular mechanisms that control its integrity. The identification of moody, a gene required for the formation and maintenance of the Drosophila BBB, provides new insight into how paracellular junctions are formed at the barrier. Meanwhile, moody also has been identified in a screen for fly mutants with altered sensitivity to cocaine, remarkably implicating the BBB in the physiological response to narcotics.Entities:
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Year: 2005 PMID： 16213208 DOI： 10.1016/j.cell.2005.09.017
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582