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Literature DB >> 16206301

Regio- and chemoselective 6'-N-derivatization of aminoglycosides: bisubstrate inhibitors as probes to study aminoglycoside 6'-N-acetyltransferases.

Feng Gao¹, Xuxu Yan, Oliver M Baettig, Albert M Berghuis, Karine Auclair.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16206301 DOI： 10.1002/anie.200501399

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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29 in total

1. Inhibitors of aminoglycoside resistance activated in cells.

Authors: Kenward Vong; Ingrid S Tam; Xuxu Yan; Karine Auclair
Journal: ACS Chem Biol Date: 2012-01-18 Impact factor: 5.100

Review 2. Solution NMR Spectroscopy for the Study of Enzyme Allostery.

Authors: George P Lisi; J Patrick Loria
Journal: Chem Rev Date: 2016-01-06 Impact factor: 60.622

3. Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside-CoA bisubstrates as mechanistic probes for aminoglycoside N-6'-acetyltransferase.

Authors: Feng Gao; Xuxu Yan; Omar Zahr; Aaron Larsen; Kenward Vong; Karine Auclair
Journal: Bioorg Med Chem Lett Date: 2008-09-06 Impact factor: 2.823

4. Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP.

Authors: Hua Xu; Subray S Hegde; John S Blanchard
Journal: Biochemistry Date: 2011-06-10 Impact factor: 3.162

5. Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme.

Authors: Lee A Freiburger; Oliver M Baettig; Tara Sprules; Albert M Berghuis; Karine Auclair; Anthony K Mittermaier
Journal: Nat Struct Mol Biol Date: 2011-01-30 Impact factor: 15.369

6. Synthesis of 4'-aminopantetheine and derivatives to probe aminoglycoside N-6'-acetyltransferase.

Authors: Xuxu Yan; T Olukayode Akinnusi; Aaron T Larsen; Karine Auclair
Journal: Org Biomol Chem Date: 2011-01-12 Impact factor: 3.876

7. Inhibition of aminoglycoside-deactivating enzymes APH(3')-IIIa and AAC(6')-Ii by amphiphilic paromomycin O2''-ether analogues.

Authors: Janek Szychowski; Jiro Kondo; Omar Zahr; Karine Auclair; Eric Westhof; Stephen Hanessian; Jeffrey W Keillor
Journal: ChemMedChem Date: 2011-09-08 Impact factor: 3.466