| Literature DB >> 1620618 |
L M Montero1, J Filipski, P Gil, J Capel, J M Martínez-Zapater, J Salinas.
Abstract
We have determined the 5-methylcytosine (5mC) content in high molecular weight DNA, from two dicot (tobacco and pea) and two monocot (wheat and maize) plant species, fractionated according to base composition. The results show that the proportion of 5mC in the genomic fractions increases linearly with their guanine + cytosine (G + C) content while the proportion of non-methylated cytosine remains almost constant. This can be interpreted as a consequence of a difference in mutation pressure related to spontaneous deamination of 5mC to thymine between the different compartments of plant genomes.Entities:
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Year: 1992 PMID: 1620618 PMCID: PMC312460 DOI: 10.1093/nar/20.12.3207
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971