Literature DB >> 16205570

Perfluoro-n-octane as a postoperative vitreoretinal tamponade in the management of giant retinal tears.

Marc Rofail1, Lawrence R Lee.   

Abstract

BACKGROUND: Despite recent advances in giant retinal tear repair, retinal redetachment remains an issue. This may be due to inadequate retinal tamponade with silicone oil or perfluorocarbon gas that allows fluid to seep back under the edge of the tear. We propose short-term postoperative retinal tamponade with perfluoro-n-octane liquid to overcome this problem. Theoretical advantages include the reduced likelihood of proliferative vitreoretinopathy. It is easier to remove than silicone oil due to its lower viscosity, and supine posturing is more manageable from a patient perspective.
METHODS: A retrospective case series of 16 giant retinal tear repairs without significant proliferative vitreoretinopathy is presented. Lens-sparing vitrectomy was performed with endolaser to the edge of the tear and the entire retinal periphery. Scleral buckling was not utilized. Perfluoro-n-octane was used as a postoperative tamponade for a mean of 16.4 days (range, 6-50 days).
RESULTS: The retina was reattached at the end of the procedure in all 16 cases. Redetachment occurred in only 1 (6.3%) of 16 cases.
CONCLUSION: Postoperative tamponade with perfluoro-n-octane may decrease the rate of redetachment in giant retinal tear repair compared with silicone oil or perfluorocarbon gas alone. We found no adverse effects directly attributable to perfluoro-n-octane.

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Year:  2005        PMID: 16205570     DOI: 10.1097/00006982-200510000-00013

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  19 in total

1.  Vitreous Substitutes.

Authors:  William Joseph Foster
Journal:  Expert Rev Ophthalmol       Date:  2008-04

2.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Xue Wang; Ajay E Kuriyan; Samuel A Abariga; Wen-Hsiang Lee
Journal:  Cochrane Database Syst Rev       Date:  2020-05-13

3.  Rapid detection of bacterial endotoxins in ophthalmic viscosurgical device materials by direct analysis in real time mass spectrometry.

Authors:  Hongli Li; Victoria M Hitchins; Samanthi Wickramasekara
Journal:  Anal Chim Acta       Date:  2016-09-29       Impact factor: 6.558

4.  Massive subretinal and subretinal pigment epithelial hemorrhage displacement with perfluorocarbon liquid using a two-step vitrectomy technique.

Authors:  Efrat Fleissig; Adiel Barak; Michaela Goldstein; Anat Loewenstein; Shulamit Schwartz
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-04-15       Impact factor: 3.117

5.  Surgical outcomes of 27-gauge pars plana vitrectomy with short-term postoperative tamponade of perfluorocarbon liquid for repair of giant retinal tears.

Authors:  Zhaotian Zhang; Yantao Wei; Xintong Jiang; Shaochong Zhang
Journal:  Int Ophthalmol       Date:  2017-06-22       Impact factor: 2.031

Review 6.  The concept of heavy tamponades-chances and limitations.

Authors:  Antonia M Joussen; David Wong
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-06-11       Impact factor: 3.117

Review 7.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Wen-Hsiang Lee; Elizabeth Ssemanda; Ann-Margret Ervin
Journal:  Cochrane Database Syst Rev       Date:  2009-10-07

Review 8.  Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

Authors:  Stephen G Schwartz; Harry W Flynn; Wen-Hsiang Lee; Xue Wang
Journal:  Cochrane Database Syst Rev       Date:  2014-02-14

9.  25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane for the repair of giant retinal tears.

Authors:  John C Randolph; Rocio I Diaz; Eric J Sigler; Jorge I Calzada; Steve Charles
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-05-12       Impact factor: 3.117

10.  Ocular tolerance and efficacy of short-term tamponade with double filling of polydimethyloxane and perfluoro-n-octane.

Authors:  Stefano Zenoni; Mario R Romano; Sonia Palmieri; Natalia Comi; Edoardo Fiorentini; Piero Fontana
Journal:  Clin Ophthalmol       Date:  2011-04-06
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