Literature DB >> 16205347

Motor recovery, functional status, and health-related quality of life in patients with complete spinal cord injuries.

Charles G Fisher1, Vanessa K Noonan, Donna E Smith, Peter C Wing, Marcel F Dvorak, Brian K Kwon, Brian Kwon.   

Abstract

STUDY
DESIGN: A retrospective cohort with cross- sectional follow-up.
OBJECTIVES: The primary objective was to determine motor recovery in patients with complete traumatic spinal cord injury (SCI). Secondary objectives included: 1) determining which factors predict local recovery, 2) assessing functional status using the Functional Independence Measure (FIM), and 3) assessing generic health-related quality of life using the Short Form-36 (SF-36). SUMMARY OF BACKGROUND DATA: Motor recovery following complete SCI has been documented in the literature; however, it has been difficult to interpret: 1) spinal shock is often not addressed; 2) the definition of complete SCI has changed over the last 10 years; and 3) few studies differentiate between local neurologic recovery in the zone of partial preservation and neurologic recovery caudal to the lesion.
METHODS: All patients admitted to Vancouver Hospital with a complete SCI between 1994 and 2001 were identified and included in the study if they remained complete following the resolution of spinal shock. Minimum 2-year follow-up consisted of an ASIA motor score, an FIM, and the SF-36.
RESULTS: Of 133 patients identified, 94 were eligible and 70 completed follow-up. For the tetraplegic patients, the average ASIA motor score was 11.9 +/- 10.7 on admission and 20.1 +/- 10.8 at follow-up, a change reflecting local recovery only. For the paraplegic patients, the average ASIA motor score was 49.3 +/- 2.4 on admission and 50.6 +/- 1.7 at follow-up.
CONCLUSIONS: Motor recovery does not occur below the zone of injury for patients with complete SCI. Varying degrees of local recovery can be expected in tetraplegic individuals.

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Mesh:

Year:  2005        PMID: 16205347     DOI: 10.1097/01.brs.0000181058.06412.a9

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  12 in total

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9.  Does intraoperative neurophysiological monitoring have predictive value for functional recovery following spinal cord injury? A case report.

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10.  Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury.

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Journal:  Neural Plast       Date:  2015-10-11       Impact factor: 3.599

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