Literature DB >> 16204576

Fecal microbiota composition and frailty.

Sandra P van Tongeren1, Joris P J Slaets, H J M Harmsen, Gjalt W Welling.   

Abstract

The relationship between fecal microbiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella (threefold) and the Faecalibacterium prausnitzii (fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.

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Year:  2005        PMID： 16204576      PMCID： PMC1265947          DOI： 10.1128/AEM.71.10.6438-6442.2005

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


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