Literature DB >> 16197667

Impact of hypoglycaemia on quality of life and productivity in type 1 and type 2 diabetes.

Ruth E Davis1, Malcolm Morrissey, John R Peters, Kim Wittrup-Jensen, Tessa Kennedy-Martin, Craig J Currie.   

Abstract

AIM: To characterise the impact of increasing severity and frequency of hypoglycaemia on utility, quality of life, primary care resource use and productivity (time away from normal activities) in people with both Type 1 and Type 2 diabetes.
METHODS: A postal survey was sent to 3200 people with diabetes. Self-reported episodes of mild, moderate, severe and nocturnal hypoglycaemia were quantified from a list of signs and symptoms. A number of instruments were used to explore the effect of frequency and severity of hypoglycaemia on quality of life and productivity.
RESULTS: There were 861 respondents for whom diabetes type was identifiable. Of these respondents, 629 (73%) experienced some form of hypoglycaemia, 516 (60%) non-exclusively experienced mild or moderate hypoglycaemia, 57 (7%) experienced severe hypoglycaemia and 191 (22%) experienced nocturnal hypoglycaemia. Quality of life and health-related utility decreased as the frequency and severity of hypoglycaemia increased. The use of primary care resources and lost productivity increased as the severity and frequency of hypoglycaemia increased. These associations were independent in multivariate analysis.
CONCLUSIONS: These findings suggest hypoglycaemia impacts heavily on the well-being, productivity and quality of life of people with diabetes, and that every effort should be made to minimise hypoglycaemia while aiming for good glycaemic control.

Entities:  

Mesh:

Year:  2005        PMID: 16197667     DOI: 10.1185/030079905X61929

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  66 in total

1.  The health-related utility and health-related quality of life of hospital-treated subjects with type 1 or type 2 diabetes with particular reference to differing severity of peripheral neuropathy.

Authors:  C J Currie; C D Poole; A Woehl; C Ll Morgan; S Cawley; M D Rousculp; M T Covington; J R Peters
Journal:  Diabetologia       Date:  2006-08-30       Impact factor: 10.122

2.  The Association of Biochemical Hypoglycemia with the Subsequent Risk of a Severe Hypoglycemic Event: Analysis of the DCCT Data Set.

Authors:  Roy W Beck; Richard M Bergenstal; Tonya D Riddlesworth; Craig Kollman
Journal:  Diabetes Technol Ther       Date:  2018-12-21       Impact factor: 6.118

3.  Experimental non-severe hypoglycaemia substantially impairs cognitive function in type 2 diabetes: a randomised crossover trial.

Authors:  Malin Nilsson; Nicole Jensen; Michael Gejl; Marianne L Bergmann; Heidi Storgaard; Mette Zander; Kamilla Miskowiak; Jørgen Rungby
Journal:  Diabetologia       Date:  2019-07-31       Impact factor: 10.122

4.  Cost-effectiveness of Continuous Glucose Monitoring for Adults With Type 1 Diabetes Compared With Self-Monitoring of Blood Glucose: The DIAMOND Randomized Trial.

Authors:  Wen Wan; M Reza Skandari; Alexa Minc; Aviva G Nathan; Aaron Winn; Parmida Zarei; Michael O'Grady; Elbert S Huang
Journal:  Diabetes Care       Date:  2018-04-12       Impact factor: 19.112

5.  Assessing the impact of non-severe hypoglycemic events and treatment in adults: development of the Treatment-Related Impact Measure-Non-severe Hypoglycemic Events (TRIM-HYPO).

Authors:  Meryl Brod; Lise Højbjerre; Donald M Bushnell; Charlotte Thim Hansen
Journal:  Qual Life Res       Date:  2015-06-21       Impact factor: 4.147

Review 6.  Mechanisms of hypoglycemia unawareness and implications in diabetic patients.

Authors:  Iciar Martín-Timón; Francisco Javier Del Cañizo-Gómez
Journal:  World J Diabetes       Date:  2015-07-10

Review 7.  Nocturnal hypoglycemia: answering the challenge with long-acting insulin analogs.

Authors:  Stephen A Brunton
Journal:  MedGenMed       Date:  2007-05-17

8.  Patient-reported outcomes following treatment with the human GLP-1 analogue liraglutide or glimepiride in monotherapy: results from a randomized controlled trial in patients with type 2 diabetes.

Authors:  B W Bode; M A Testa; M Magwire; P M Hale; M Hammer; L Blonde; A Garber
Journal:  Diabetes Obes Metab       Date:  2010-07       Impact factor: 6.577

9.  Factors associated with psychological and behavioral functioning in people with type 2 diabetes living in France.

Authors:  Stephanie Boini; Marie-Line Erpelding; Anne Fagot-Campagna; Mounir Mesbah; Judith Chwalow; Alfred Penfornis; Vincent Coliche; Etienne Mollet; Keith Meadows; Serge Briançon
Journal:  Health Qual Life Outcomes       Date:  2010-11-02       Impact factor: 3.186

10.  Outcomes of adding second hypoglycemic drug after metformin monotherapy failure among type 2 diabetes in Hungary.

Authors:  György Jermendy; Diana Erdesz; Laszlo Nagy; Don Yin; Hemant Phatak; Sudeep Karve; Samuel Engel; Rajesh Balkrishnan
Journal:  Health Qual Life Outcomes       Date:  2008-10-31       Impact factor: 3.186

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