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Literature DB >> 16189122

AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters.

Xian-Zhong Su¹, Jing Chen, Tohru Mizushima, Teruo Kuroda, Tomofusa Tsuchiya.

Abstract

We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H(+)-coupled multidrug efflux pump and a unique member of the MATE family.

Entities: Gene Species

Mesh：

Substances：

Year: 2005 PMID： 16189122 PMCID： PMC1251516 DOI： 10.1128/AAC.49.10.4362-4364.2005

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

24 in total

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Journal: Antimicrob Agents Chemother Date: 2001-12 Impact factor: 5.191

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Journal: J Bacteriol Date: 2002-01 Impact factor: 3.490

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Journal: Mol Microbiol Date: 1999-01 Impact factor: 3.501

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Journal: Clin Microbiol Rev Date: 1996-04 Impact factor: 26.132

6. Imipenem resistance among Acinetobacter baumannii: association with reduced expression of a 33-36 kDa outer membrane protein.

Authors: R B Clark
Journal: J Antimicrob Chemother Date: 1996-08 Impact factor: 5.790

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Authors: Jong Hwa Yum; Keonsoo Yi; Hyukmin Lee; Dongeun Yong; Kyungwon Lee; June Myung Kim; Gian Maria Rossolini; Yunsop Chong
Journal: J Antimicrob Chemother Date: 2002-05 Impact factor: 5.790

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Journal: J Med Microbiol Date: 1998-05 Impact factor: 2.472

9. Evidence for chloramphenicol/H+ antiport in Cmr (MdfA) system of Escherichia coli and properties of the antiporter.

Authors: T Mine; Y Morita; A Kataoka; T Mizushima; T Tsuchiya
Journal: J Biochem Date: 1998-07 Impact factor: 3.387

10. NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus and its homolog in Escherichia coli.

Authors: Y Morita; K Kodama; S Shiota; T Mine; A Kataoka; T Mizushima; T Tsuchiya
Journal: Antimicrob Agents Chemother Date: 1998-07 Impact factor: 5.191

62 in total

Review 1. Global challenge of multidrug-resistant Acinetobacter baumannii.

Authors: Federico Perez; Andrea M Hujer; Kristine M Hujer; Brooke K Decker; Philip N Rather; Robert A Bonomo
Journal: Antimicrob Agents Chemother Date: 2007-07-23 Impact factor: 5.191

Review 2. Efflux-mediated drug resistance in bacteria: an update.

Authors: Xian-Zhi Li; Hiroshi Nikaido
Journal: Drugs Date: 2009-08-20 Impact factor: 9.546

Review 3. Xenobiotic efflux in bacteria and fungi: a genomics update.

Authors: Ravi D Barabote; Jose Thekkiniath; Richard E Strauss; Govindsamy Vediyappan; Joe A Fralick; Michael J San Francisco
Journal: Adv Enzymol Relat Areas Mol Biol Date: 2011

4. Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter.

Authors: Kevin L Jagessar; Derek P Claxton; Richard A Stein; Hassane S Mchaourab
Journal: Proc Natl Acad Sci U S A Date: 2020-02-19 Impact factor: 11.205

5. The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance.

Authors: Kevin L Jagessar; Hassane S Mchaourab; Derek P Claxton
Journal: J Biol Chem Date: 2019-07-09 Impact factor: 5.157

6. Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray.

Authors: Sébastien Coyne; Ghislaine Guigon; Patrice Courvalin; Bruno Périchon
Journal: Antimicrob Agents Chemother Date: 2009-11-02 Impact factor: 5.191

10. Optimization of 4-Substituted Benzenesulfonamide Scaffold To Reverse Acinetobacter baumannii Serum-Adaptive Efflux Associated Antibiotic Tolerance.

Authors: Michaelle Chojnacki; Xufeng Cao; Mikaeel Young; Rebecca N Fritz; Paul M Dunman; Daniel P Flaherty
Journal: ChemMedChem Date: 2020-08-13 Impact factor: 3.466