Literature DB >> 16189043

Prehospital activated charcoal: the way forward.

S L Greene1, M Kerins, N O'Connor.   

Abstract

OBJECTIVES: Single dose activated charcoal (SDAC) may be an effective method of gastric decontamination when administered to patients within an hour of drug overdose. However, few patients who may benefit from this treatment attend an emergency department within this timeframe. The authors sought to determine the current attitudes of ambulance NHS trusts to recent recommendations that the administration of SDAC should be considered as a prehospital therapy.
METHODS: A postal questionnaire was used to determine the current level of use of prehospital activated charcoal by ambulance NHS trusts, the incidence of associated complications, and barriers preventing the routine use of prehospital SDAC.
RESULTS: A completed questionnaire was returned by 36 of the 39 ambulance NHS trusts in the UK (response rate 92%). Currently none of the trusts that responded to the questionnaire provides prehospital SDAC as an intervention. The most common barriers to the provision of prehospital SDAC are the current lack of evidence in the medical literature proving it is effective in improving patient outcome and the lack of a recognised protocol for its administration. Other issues included concerns regarding potential complications, ambulance turnaround times, lack of availability of SDAC, and lack of funding.
CONCLUSIONS: A lack of published evidence proving efficacy remains the most important factor in preventing the routine administration of SDAC to appropriate patients in the prehospital environment. Further research in this setting is required to determine the usefulness of this therapy.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16189043      PMCID: PMC1726563          DOI: 10.1136/emj.2005.024968

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  7 in total

1.  How feasible is it to conform to the European guidelines on administration of activated charcoal within one hour of an overdose?

Authors:  A Karim; S Ivatts; P Dargan; A Jones
Journal:  Emerg Med J       Date:  2001-09       Impact factor: 2.740

2.  Activated charcoal reduces the need for N-acetylcysteine treatment after acetaminophen (paracetamol) overdose.

Authors:  N A Buckley; I M Whyte; D L O'Connell; A H Dawson
Journal:  J Toxicol Clin Toxicol       Date:  1999

Review 3.  Position paper: Single-dose activated charcoal.

Authors:  P A Chyka; D Seger; E P Krenzelok; J A Vale
Journal:  Clin Toxicol (Phila)       Date:  2005       Impact factor: 4.467

4.  Prehospital gastrointestinal decontamination of toxic ingestions: a missed opportunity.

Authors:  P M Wax; D J Cobaugh
Journal:  Am J Emerg Med       Date:  1998-03       Impact factor: 2.469

5.  Out-of-hospital administration of activated charcoal by emergency medical services.

Authors:  Ari O Alaspää; Markku J Kuisma; Kalle Hoppu; Pertti J Neuvonen
Journal:  Ann Emerg Med       Date:  2005-02       Impact factor: 5.721

6.  The potential role of prehospital administration of activated charcoal.

Authors:  S Thakore; N Murphy
Journal:  Emerg Med J       Date:  2002-01       Impact factor: 2.740

7.  Single-dose oral activated charcoal in the treatment of the self-poisoned patient: a prospective, randomized, controlled trial.

Authors:  Kevin S Merigian; Kari E Blaho
Journal:  Am J Ther       Date:  2002 Jul-Aug       Impact factor: 2.688

  7 in total
  1 in total

1.  Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability.

Authors:  Rudolf Pfab; Sabrina Schmoll; Gabriele Dostal; Jochen Stenzel; Alexander Hapfelmeier; Florian Eyer
Journal:  Toxicol Rep       Date:  2016-12-31
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.