Literature DB >> 16188781

Aplasia cutis congenita of the scalp: how much therapy is necessary in large defects?

B Bernbeck1, J Schwabe, A Groninger, J Schaper, H Messing-Jünger, E Mayatepek, T Rosenbaum.   

Abstract

AIM: To show that local antibiotic management and a regular inspection of aplasia cutis congenita of the skull can give an excellent result.
METHOD: This case reports a girl born with aplasia cutis congenita of the skull presenting with a large aplasia of the epidermis, dermis, subcutaneous tissue and galea, including a bone defect without any additional risk factor, e.g. early eschar formation, cerebrospinal fluid leakage or uncommon dural blood vessels.
RESULTS: A primarily conservative treatment with local wet and antibiotic dressings together with a systemic antibiotic treatment for the first 2 wk led to an excellent result and thus prevented untimely operative and peri-operative procedures.
CONCLUSIONS: Here we have shown that conservative treatment might be an option, even if the wound diameter is greater than 1 cm(2), to prevent infants from any untimely operative procedure with an elevated operative risk if any additional risk factors are excluded.

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Year:  2005        PMID: 16188781     DOI: 10.1111/j.1651-2227.2005.tb01977.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  6 in total

Review 1.  Aplasia cutis congenita of the scalp: is there a better treatment strategy?

Authors:  Ricardo Santos de Oliveira; Carlos Eduardo Barros Jucá; Antônio Lopes Lins-Neto; Maria Aparecida do Carmo Rego; Jaime Farina; Helio Rubens Machado
Journal:  Childs Nerv Syst       Date:  2006-04-26       Impact factor: 1.475

2.  Dilemmas and challenges in the management of a neonate with Adams-Oliver syndrome with infected giant aplasia cutis lesion and exsanguination: a case-based update.

Authors:  Suhas Udayakumaran; Jimmy Mathew; Dilip Panikar
Journal:  Childs Nerv Syst       Date:  2012-12-29       Impact factor: 1.475

3.  Two different management modalities in a two sibling case report of Adams Oliver syndrome.

Authors:  Nada Al-Hadithy; Joanna Mennie; Ken Stewart
Journal:  BMJ Case Rep       Date:  2011-12-21

4.  Conservative Healing of an 11 × 9-cm Aplasia Cutis Congenita of the Scalp with Bone Defect.

Authors:  Victoria Fröjd; Giovanni Maltese; Lars Kölby; Peter Tarnow
Journal:  J Neurol Surg Rep       Date:  2014-08-11

5.  Aplasia cutis congenita: a conservative approach of a case with large, extensive skin, and underlying skull defect.

Authors:  Dalila Rocha; Joana Rodrigues; Jorge Sales Marques; Rui Pinto; Anabela Gomes
Journal:  Clin Case Rep       Date:  2015-09-02

6.  Treatment of a Large Skull Defect and Brain Herniation in a Newborn With Adams-Oliver Syndrome.

Authors:  Kim M Wehrens; Frank De Jongh; M P Ter Laak; E M Cornips; Rrwj Van der Hulst
Journal:  Cureus       Date:  2020-02-19
  6 in total

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