Literature DB >> 16187413

Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.).

Guo-Qing He1, Hao-Ping Xiong, Qi-He Chen, Hui Ruan, Zhao-Yue Wang, Lonseny Traoré.   

Abstract

Waste hops are good sources of flavonoids. Extraction of flavonoids from waste hops (SC-CO(2) extracted hops) using supercritical fluids technology was investigated. Various temperatures, pressures and concentrations of ethanol (modifier) and the ratio (w/w) of solvent to material were tested in this study. The results of single factor and orthogonal experiments showed that at 50 degrees C, 25 MPa, the ratio of solvent to material (50%), ethanol concentration (80%) resulted in maximum extraction yield flavonoids (7.8 mg/g). HPLC-MS analysis of the extracts indicated that flavonoids obtained were xanthohumol, the principal prenylflavonoid in hops.

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Year:  2005        PMID： 16187413      PMCID： PMC1390442          DOI： 10.1631/jzus.2005.B0999

Source DB:  PubMed          Journal:  J Zhejiang Univ Sci B        ISSN： 1673-1581            Impact factor:   3.066


  7 in total

1.  The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids.

Authors:  S R Milligan; J C Kalita; V Pocock; V Van De Kauter; J F Stevens; M L Deinzer; H Rong; D De Keukeleire
Journal:  J Clin Endocrinol Metab       Date:  2000-12       Impact factor: 5.958

Review 2.  Xanthohumol and related prenylflavonoids from hops and beer: to your good health!

Authors:  Jan F Stevens; Jonathan E Page
Journal:  Phytochemistry       Date:  2004-05       Impact factor: 4.072

3.  Bone resorption inhibitors from hop extract.

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Authors:  C L Miranda; G L Aponso; J F Stevens; M L Deinzer; D R Buhler
Journal:  Cancer Lett       Date:  2000-02-28       Impact factor: 8.679

5.  Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry.

Authors:  J F Stevens; A W Taylor; M L Deinzer
Journal:  J Chromatogr A       Date:  1999-02-05       Impact factor: 4.759

6.  Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.

Authors:  C L Miranda; J F Stevens; A Helmrich; M C Henderson; R J Rodriguez; Y H Yang; M L Deinzer; D W Barnes; D R Buhler
Journal:  Food Chem Toxicol       Date:  1999-04       Impact factor: 6.023

7.  Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus.

Authors:  N Tabata; M Ito; H Tomoda; S Omura
Journal:  Phytochemistry       Date:  1997-10       Impact factor: 4.072
  7 in total
  11 in total

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Journal:  J Zhejiang Univ Sci B       Date:  2012-06       Impact factor: 3.066

2.  A comparative study of conventional and supercritical fluid extraction methods for the recovery of secondary metabolites from Syzygium campanulatum Korth.

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5.  Analysis and comparison of the active components and antioxidant activities of extracts from Abelmoschus esculentus L.

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7.  Simultaneous Extraction Optimization and Analysis of Flavonoids from the Flowers of Tabernaemontana heyneana by High Performance Liquid Chromatography Coupled to Diode Array Detector and Electron Spray Ionization/Mass Spectrometry.

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Review 8.  The Application of Supercritical Fluid Extraction in Phenolic Compounds Isolation from Natural Plant Materials.

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9.  Development of Phaleria macrocarpa (Scheff.) Boerl Fruits Using Response Surface Methodology Focused on Phenolics, Flavonoids and Antioxidant Properties.

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10.  Optimization of Glycerol-Water Extraction of Selected Bioactive Compounds from Peppermint and Common Nettle.

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