UNLABELLED: Postpartum hemorrhage (PPH) is one of the top 5 causes of maternal mortality in developed and developing countries. The incidence of PPH is 40% after vaginal delivery and 30% after cesarean section. Criteria for PPH are based on the amount of blood loss. In clinical obstetrics, exact measurement of blood loss is often difficult. The most important treatment of PPH is red blood cell (RBC) transfusion. In the past few years, increasing concern has arisen about this treatment. Despite the introduction of several new guidelines, transfusion criteria still vary widely between clinicians. The decision whether to prescribe RBC transfusion is mostly based on postpartum hemoglobin (Hb) values. RBC transfusion should be aimed to reduce morbidity and especially to improve health-related quality of life (HRQoL). In this review, etiology, epidemiology, treatment, and prevention of postpartum hemorrhage are described. Special attention is given to the role of RBC transfusion in the treatment of PPH and the effects of RBC transfusion on HRQoL. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this article, the reader should be able to summarize the new guidelines related to transfusion criteria, explain the importance of reducing morbidity related to improving quality of life issues, and list infectious and noninfectious complications of a red blood cell transfusion.
UNLABELLED: Postpartum hemorrhage (PPH) is one of the top 5 causes of maternal mortality in developed and developing countries. The incidence of PPH is 40% after vaginal delivery and 30% after cesarean section. Criteria for PPH are based on the amount of blood loss. In clinical obstetrics, exact measurement of blood loss is often difficult. The most important treatment of PPH is red blood cell (RBC) transfusion. In the past few years, increasing concern has arisen about this treatment. Despite the introduction of several new guidelines, transfusion criteria still vary widely between clinicians. The decision whether to prescribe RBC transfusion is mostly based on postpartum hemoglobin (Hb) values. RBC transfusion should be aimed to reduce morbidity and especially to improve health-related quality of life (HRQoL). In this review, etiology, epidemiology, treatment, and prevention of postpartum hemorrhage are described. Special attention is given to the role of RBC transfusion in the treatment of PPH and the effects of RBC transfusion on HRQoL. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this article, the reader should be able to summarize the new guidelines related to transfusion criteria, explain the importance of reducing morbidity related to improving quality of life issues, and list infectious and noninfectious complications of a red blood cell transfusion.
Authors: Evan M Bloch; Robert L Crookes; Jennifer Hull; Sue Fawcus; Rajesh Gangaram; John Anthony; Charlotte Ingram; Solomuzi Ngcobo; Julie Croxford; Darryl V Creel; Edward L Murphy Journal: Transfusion Date: 2015-03-16 Impact factor: 3.157
Authors: Babette W Prick; Eric A P Steegers; A J Gerard Jansen; Wim C J Hop; Marie-Louise Essink-Bot; Nina C J Peters; Carin A Uyl-de Groot; Dimitri N M Papatsonis; Bettina M C Akerboom; Godfried C H Metz; Henk A Bremer; Aren J van Loon; Rob H Stigter; Joris A M van der Post; Marcel van Alphen; Martina Porath; Robbert J P Rijnders; Marc E A Spaanderman; Daniela H Schippers; Kitty W M Bloemenkamp; Kim E Boers; Hubertina C J Scheepers; Frans J M E Roumen; Anneke Kwee; Nico W E Schuitemaker; Ben Willem J Mol; Dick J van Rhenen; Johannes J Duvekot Journal: BMC Pregnancy Childbirth Date: 2010-12-16 Impact factor: 3.007
Authors: C A G Holleboom; J van Eyck; S V Koenen; I A M Kreuwel; F Bergwerff; E C Creutzberg; H W Bruinse Journal: Arch Gynecol Obstet Date: 2013-01-18 Impact factor: 2.344
Authors: Joey de Vogel; Roger Heydanus; Annemarie G M Mulders; Dina J C Smalbraak; Dimitri N M Papatsonis; Bastiaan M Gerritse Journal: AJP Rep Date: 2011-11-11