Literature DB >> 1618635

Colocalization of protein kinase C beta-subtype and calcitonin gene-related peptide in rat spinal cord.

M Hietanen-Peltola1.   

Abstract

Colocalization of calcitonin gene-related peptide (CGRP) and protein kinase C beta-subtype (PKC-beta) like immunoreactivities (LI) and the subcellular localization of CGRP-LI were studied in the ventral horn of rat spinal cord. Ultrastructurally CGRP-LI was localized on the membranes of the Golgi-complexes, in multivesicular bodies and in vesicles adjacent to the Golgi-complex in motoneuron perikarya. The colocalization of PKC-beta and CGRP-LI was detected in most of the ventral horn motoneurons. However, few motoneurons were only PKC-beta-immunoreactive. These results suggest that PKC-beta may be involved in the regulation of CGRP release from motoric axon terminals.

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Year:  1992        PMID： 1618635     DOI： 10.1007/bf00271277

Source DB:  PubMed          Journal:  Histochemistry        ISSN： 0301-5564


  31 in total

1.  Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.

Authors:  P R Girard; G J Mazzei; J G Wood; J F Kuo
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

2.  Stimulation of spontaneous transmitter release by the phorbol ester, 12-O-tetradecanoylphorbol-13-acetate, an activator of protein kinase C.

Authors:  S J Publicover
Journal:  Brain Res       Date:  1985-04-29       Impact factor: 3.252

3.  Immunocytochemical study of the relations of acetylcholinesterase, enkephalin-, substance P-, choline acetyltransferase- and calcitonin gene-related peptide-immunoreactive structures in the ventral horn of rat spinal cord.

Authors:  M Hietanen; M Pelto-Huikko; L Rechardt
Journal:  Histochemistry       Date:  1990

Review 4.  Studies and perspectives of protein kinase C.

Authors:  Y Nishizuka
Journal:  Science       Date:  1986-07-18       Impact factor: 47.728

5.  Effects of calcitonin gene-related peptide on neuromuscular transmission in the isolated rat diaphragm.

Authors:  T Ohhashi; D M Jacobowitz
Journal:  Peptides       Date:  1988 May-Jun       Impact factor: 3.750

6.  Calcitonin gene-related peptide messenger RNA is expressed in sensory neurones of the dorsal root ganglia and also in spinal motoneurones in man and rat.

Authors:  S J Gibson; J M Polak; A Giaid; Q A Hamid; S Kar; P M Jones; P Denny; S Legon; S G Amara; R K Craig
Journal:  Neurosci Lett       Date:  1988-09-12       Impact factor: 3.046

7.  Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane.

Authors:  A S Kraft; W B Anderson
Journal:  Nature       Date:  1983 Feb 17-23       Impact factor: 49.962

8.  Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products.

Authors:  S G Amara; V Jonas; M G Rosenfeld; E S Ong; R M Evans
Journal:  Nature       Date:  1982-07-15       Impact factor: 49.962

9.  Distinct patterns of expression of different protein kinase C mRNAs in rat tissues.

Authors:  S J Brandt; J E Niedel; R M Bell; W S Young
Journal:  Cell       Date:  1987-04-10       Impact factor: 41.582

10.  Cloning and expression of multiple protein kinase C cDNAs.

Authors:  J L Knopf; M H Lee; L A Sultzman; R W Kriz; C R Loomis; R M Hewick; R M Bell
Journal:  Cell       Date:  1986-08-15       Impact factor: 41.582
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  1 in total

1.  Nephrilin peptide modulates a neuroimmune stress response in rodent models of burn trauma and sepsis.

Authors:  Desmond D Mascarenhas; Amina Elayadi; Baljit K Singh; Anesh Prasai; Sachin D Hegde; David N Herndon; Celeste C Finnerty
Journal:  Int J Burns Trauma       Date:  2013-11-01
  1 in total

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