| Literature DB >> 1618300 |
M Tsuda1, Y Sei, M Yamamura, M Yamamoto, Y Shinohara.
Abstract
A new mutant alpha-1-antichymotrypsin (variant ACT) was found by direct sequencing and PCR-single strand conformation polymorphism (PCR-SSCP). This variant ACT was a point mutation of exon V of ACT, with the substitution of Met by Val. Four out of six individuals with this variant ACT had occlusive-cerebrovascular disease, leading to one hypothesis that there might be an association between this mutation and occlusive-cerebrovascular disease.Entities:
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Year: 1992 PMID： 1618300 DOI： 10.1016/0014-5793(92)80590-d
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124