Literature DB >> 1618161

The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer?

K B Horwitz1.   

Abstract

Entities:  

Keywords:  Americas; Animals, Laboratory; Biology; Breast Cancer; Cancer; Clinical Research; Clinical Trials; Critique; Developed Countries; Diseases; Endocrine System; Ethics; Hormone Antagonists; Hormone Receptors; Hormones; Literature Review; Membrane Proteins; Neoplasms; North America; Northern America; Obstacles; Organization And Administration; Physiology; Progestational Hormones; Progesterone; Research Methodology; Ru-486--beneficial effects; Ru-486--pharmacodynamics; Ru-486--side effects; Treatment; United States

Mesh：

Substances：

Year:  1992        PMID： 1618161     DOI： 10.1210/edrv-13-2-146

Source DB:  PubMed          Journal:  Endocr Rev        ISSN： 0163-769X            Impact factor:   19.871


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  38 in total

Review 1.  Use of PRKO mice to study the role of progesterone in mammary gland development.

Authors:  R C Humphreys; J P Lydon; B W O'Malley; J M Rosen
Journal:  J Mammary Gland Biol Neoplasia       Date:  1997-10       Impact factor: 2.673

Review 2.  The future of antihormone therapy: innovations based on an established principle.

Authors:  K Parczyk; M R Schneider
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

3.  Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.

Authors:  A M Bamberger; C M Bamberger; B Gellersen; H M Schulte
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

4.  Comparison of the effects of antiprogestins RU38486, ZK98299 and ORG31710 on periovulatory hypophysial, ovarian and adrenal hormone secretion in the rat.

Authors:  J E Sánchez-Criado; M Tébar; C Bellido; F H de Jong
Journal:  J Endocrinol Invest       Date:  2000-03       Impact factor: 4.256

5.  Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin.

Authors:  Z Liu; J Wong; S Y Tsai; M J Tsai; B W O'Malley
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-16       Impact factor: 11.205

6.  Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells.

Authors:  Emily J Faivre; Carol A Lange
Journal:  Mol Cell Biol       Date:  2006-10-30       Impact factor: 4.272

Review 7.  Steroid receptor domain conformations and hormone antagonism.

Authors:  M K Agarwal
Journal:  Naturwissenschaften       Date:  1994-03

8.  A and B forms of the androgen receptor are present in human genital skin fibroblasts.

Authors:  C M Wilson; M J McPhaul
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

9.  Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.

Authors:  C J Whelan; S C Hughes; G P Wren
Journal:  Inflamm Res       Date:  1995-03       Impact factor: 4.575

Review 10.  Mechanisms of hormone resistance in breast cancer.

Authors:  K B Horwitz
Journal:  Breast Cancer Res Treat       Date:  1993       Impact factor: 4.872
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