Literature DB >> 16180831

Anti-inflammatory sesquiterpene-quinones from the New Zealand sponge Dysidea cf. cristagalli.

Catherine E McNamara1, Lesley Larsen, Nigel B Perry, Jacquie L Harper, Michael V Berridge, Elizabeth W Chia, Michelle Kelly, Victoria L Webb.   

Abstract

The inhibition of superoxide production by human neutrophils has been used to screen New Zealand's unique biota for anti-inflammatory natural products. Bioactivity-directed isolation on an extract of the sponge Dysidea cf. cristagalli led to a new sesquiterpene-quinone (4) with anti-inflammatory activity, plus acetylated hydroquinone (3). These compounds inhibited superoxide production in vitro with IC50's of 3 microM (3) and 11 microM (4).

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Year:  2005        PMID： 16180831     DOI： 10.1021/np050171n

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Three new sesquiterpene aminoquinones from a Vietnamese Spongia sp. and their biological activities.

Authors:  Takuya Ito; Hien Minh Nguyen; Nwet Nwet Win; Hung Quoc Vo; Hoai Thi Nguyen; Hiroyuki Morita
Journal:  J Nat Med       Date:  2017-09-22       Impact factor: 2.343

Review 2.  Marine pharmacology in 2005-2006: antitumour and cytotoxic compounds.

Authors:  Alejandro M S Mayer; Kirk R Gustafson
Journal:  Eur J Cancer       Date:  2008-08-11       Impact factor: 9.162

Review 3.  Marine pharmacology in 2005-6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Roberto G S Berlinck; Mark T Hamann
Journal:  Biochim Biophys Acta       Date:  2009-03-19

4.  Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways.

Authors:  Shun-Chin Yang; Ping-Jyun Sung; Chwan-Fwu Lin; Jimmy Kuo; Chun-Yu Chen; Tsong-Long Hwang
Journal:  PLoS One       Date:  2014-12-04       Impact factor: 3.240

5.  Antimicrobial activities of secondary metabolites and phylogenetic study of sponge endosymbiotic bacteria, Bacillus sp. at Agatti Island, Lakshadweep Archipelago.

Authors:  Gopi Mohan; Ajith Kumar Thipparamalai Thangappanpillai; Balagurunathan Ramasamy
Journal:  Biotechnol Rep (Amst)       Date:  2016-06-08

6.  Xishaeleganins A-D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans.

Authors:  Bao Chen; Qingmin Zhao; Yu-Cheng Gu; Lefu Lan; Chang-Yun Wang; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2022-02-01       Impact factor: 5.118

Review 7.  Meroterpenes from marine invertebrates: structures, occurrence, and ecological implications.

Authors:  Marialuisa Menna; Concetta Imperatore; Filomena D'Aniello; Anna Aiello
Journal:  Mar Drugs       Date:  2013-05-17       Impact factor: 5.118
  7 in total

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