BACKGROUND: This study was carried out to determine the true prevalence of bicuspid aortic valve (BAV) in newborns, which has not yet been determined. METHODS: One thousand seventy five live born neonates (567 male neonates, 508 female neonates; gestational ages ranging from 27 to 42 weeks, and birth weights ranging from 720 to 4,780 g) were screened by transthoracic 2-dimensional echocardiography to assess the prevalence of BAV. RESULTS AND CONCLUSION: BAV was identified in a prevalence of 4.6 in 1,000 live births. The prevalence of BAV by sex was 7.1 of 1,000 in male neonates, and 1.9 of 1,000 in female neonates. All newborns with BAV were asymptomatic. Mild aortic regurgitation was found in only 1 neonate with BAV. Because BAV may result in aortic valvular stenosis and/or regurgitation, a recommendation of regular follow-ups and antibiotic prophylaxis for infective endocarditis should be necessary.
BACKGROUND: This study was carried out to determine the true prevalence of bicuspid aortic valve (BAV) in newborns, which has not yet been determined. METHODS: One thousand seventy five live born neonates (567 male neonates, 508 female neonates; gestational ages ranging from 27 to 42 weeks, and birth weights ranging from 720 to 4,780 g) were screened by transthoracic 2-dimensional echocardiography to assess the prevalence of BAV. RESULTS AND CONCLUSION: BAV was identified in a prevalence of 4.6 in 1,000 live births. The prevalence of BAV by sex was 7.1 of 1,000 in male neonates, and 1.9 of 1,000 in female neonates. All newborns with BAV were asymptomatic. Mild aortic regurgitation was found in only 1 neonate with BAV. Because BAV may result in aortic valvular stenosis and/or regurgitation, a recommendation of regular follow-ups and antibiotic prophylaxis for infective endocarditis should be necessary.
Authors: Ratnasari Padang; Paul G Bannon; Richmond Jeremy; David R Richmond; Christopher Semsarian; Michael Vallely; Michael Wilson; Tristan D Yan Journal: Ann Cardiothorac Surg Date: 2013-01
Authors: Joanna L d'Arcy; Sean Coffey; Margaret A Loudon; Andrew Kennedy; Jonathan Pearson-Stuttard; Jacqueline Birks; Eleni Frangou; Andrew J Farmer; David Mant; Jo Wilson; Saul G Myerson; Bernard D Prendergast Journal: Eur Heart J Date: 2016-06-26 Impact factor: 29.983
Authors: Mary Ella Pierpont; Martina Brueckner; Wendy K Chung; Vidu Garg; Ronald V Lacro; Amy L McGuire; Seema Mital; James R Priest; William T Pu; Amy Roberts; Stephanie M Ware; Bruce D Gelb; Mark W Russell Journal: Circulation Date: 2018-11-20 Impact factor: 29.690