Literature DB >> 16168498

Moving past proliferation: new roles for Cdh1-APC in postmitotic neurons.

Judith Stegmüller1, Azad Bonni.   

Abstract

Nearly ten years after its discovery as a crucial cell-cycle-regulated ubiquitin ligase, the anaphase-promoting complex (APC) is making a debut in neurobiology. During the past year, some of the mystery surrounding a potential function for APC in the brain has been unveiled. Recent studies have defined novel roles for APC in the regulation of axonal growth and patterning, as well as in synaptic development and function. With this strong beginning for APC in neurobiology, the months and years to come are likely to bring many more insights into how neuronal APC contributes to biological processes in brain development and disease.

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Year:  2005        PMID: 16168498     DOI: 10.1016/j.tins.2005.09.003

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN: 0166-2236            Impact factor:   13.837


  21 in total

1.  A FOXO-Pak1 transcriptional pathway controls neuronal polarity.

Authors:  Luis de la Torre-Ubieta; Brice Gaudillière; Yue Yang; Yoshiho Ikeuchi; Tomoko Yamada; Sara DiBacco; Judith Stegmüller; Ulrich Schüller; Dervis A Salih; David Rowitch; Anne Brunet; Azad Bonni
Journal:  Genes Dev       Date:  2010-04-15       Impact factor: 11.361

2.  Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons.

Authors:  A Tomashevski; D R Webster; P Grammas; M Gorospe; I I Kruman
Journal:  Cell Death Differ       Date:  2010-01-29       Impact factor: 15.828

3.  TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis.

Authors:  Judith Stegmüller; Mai Anh Huynh; Zengqiang Yuan; Yoshiyuki Konishi; Azad Bonni
Journal:  J Neurosci       Date:  2008-02-20       Impact factor: 6.167

4.  APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit.

Authors:  Zhen Ping; Ratna Lim; Tarig Bashir; Michele Pagano; Daniele Guardavaccaro
Journal:  Cell Cycle       Date:  2012-05-15       Impact factor: 4.534

Review 5.  Is Cytoplasmic PTEN a Specific Target for Neuronal Survival?

Authors:  Anand Krishnan; Douglas W Zochodne
Journal:  Mol Neurobiol       Date:  2014-11-09       Impact factor: 5.590

6.  The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain.

Authors:  Xiaoying Chen; Ayan Chanda; Yoshiho Ikeuchi; Xiaoqing Zhang; Jared V Goodman; Naveen C Reddy; Shahriyar P Majidi; Dennis Y Wu; Sarah E Smith; Abigail Godec; Anna Oldenborg; Harrison W Gabel; Guoyan Zhao; Shirin Bonni; Azad Bonni
Journal:  J Neurosci       Date:  2018-11-13       Impact factor: 6.167

7.  Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.

Authors:  Mark D J Gurden; Andrew J Holland; Wouter van Zon; Anthony Tighe; Mailys A Vergnolle; Douglas A Andres; H Peter Spielmann; Marcos Malumbres; Rob M F Wolthuis; Don W Cleveland; Stephen S Taylor
Journal:  J Cell Sci       Date:  2010-01-05       Impact factor: 5.285

8.  Destroy to create: E3 ubiquitin ligases in neurogenesis.

Authors:  Judith Stegmüller; Azad Bonni
Journal:  F1000 Biol Rep       Date:  2010-05-24

Review 9.  Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity.

Authors:  Tomoko Yamada; Yue Yang; Azad Bonni
Journal:  Trends Neurosci       Date:  2013-01-17       Impact factor: 13.837

Review 10.  The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity.

Authors:  Yue Yang; Albert H Kim; Azad Bonni
Journal:  Curr Opin Neurobiol       Date:  2010-01-07       Impact factor: 6.627

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