Literature DB >> 16159196

Identification of benzalkonium chloride in commercial grapefruit seed extracts.

Gary R Takeoka1, Lan T Dao, Rosalind Y Wong, Leslie A Harden.   

Abstract

Commercial grapefruit seed extracts (GSE) were extracted with chloroform. The solvent was evaporated, and the resulting solid was subsequently analyzed by high-performance liquid chromatography (HPLC), electrospray ionization mass spectrometry (ESI/MS), tandem mass spectrometry (ESI/MS/MS), and elemental analysis (by proton-induced X-ray emission analysis). Three major constituents were observed by HPLC and were identified as benzyldimethyldodecylammonium chloride, benzyldimethyltetradecylammonium chloride, and benzyldimethylhexadecylammonium chloride. This mixture of homologues is commonly known as benzalkonium chloride, a widely used synthetic antimicrobial ingredient used in cleaning and disinfection agents.

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Year:  2005        PMID： 16159196     DOI： 10.1021/jf0514064

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  9 in total

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Journal:  J Am Soc Mass Spectrom       Date:  2010-08-20       Impact factor: 3.109

2.  Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis.

Authors:  Josi Herron; Rosalyn C Reese; Keri A Tallman; Rohini Narayanaswamy; Ned A Porter; Libin Xu
Journal:  Toxicol Sci       Date:  2016-02-26       Impact factor: 4.849

3.  Ameliorative effect of grapefruit juice on amiodarone-induced cytogenetic and testicular damage in albino rats.

Authors:  Saber Abdelruhman Sakr; Mohamed El-Said Zoil; Samraa Samy El-Shafey
Journal:  Asian Pac J Trop Biomed       Date:  2013-07

4.  Air and Surface Sampling Method for Assessing Exposures to Quaternary Ammonium Compounds Using Liquid Chromatography Tandem Mass Spectrometry.

Authors:  Ryan F LeBouf; Mohammed Abbas Virji; Anand Ranpara; Aleksandr B Stefaniak
Journal:  Ann Work Expo Health       Date:  2017-07-01       Impact factor: 2.179

5.  Metabolism of Benzalkonium Chlorides by Human Hepatic Cytochromes P450.

Authors:  Ryan P Seguin; Josi M Herron; Vanessa A Lopez; Joseph L Dempsey; Libin Xu
Journal:  Chem Res Toxicol       Date:  2019-12-03       Impact factor: 3.739

6.  Multi-omics investigation reveals benzalkonium chloride disinfectants alter sterol and lipid homeostasis in the mouse neonatal brain.

Authors:  Josi M Herron; Kelly M Hines; Hideaki Tomita; Ryan P Seguin; Julia Yue Cui; Libin Xu
Journal:  Toxicol Sci       Date:  2019-06-14       Impact factor: 4.849

7.  Inhibitory effect of grapefruit seed extract (GSE) on avian pathogens.

Authors:  Miyuki Komura; Mayuko Suzuki; Natthanan Sangsriratanakul; Mariko Ito; Satoru Takahashi; Md Shahin Alam; Mizuki Ono; Chisato Daio; Dany Shoham; Kazuaki Takehara
Journal:  J Vet Med Sci       Date:  2019-02-04       Impact factor: 1.267

Review 8.  Antimicrobial edible films and coatings for meat and meat products preservation.

Authors:  Irais Sánchez-Ortega; Blanca E García-Almendárez; Eva María Santos-López; Aldo Amaro-Reyes; J Eleazar Barboza-Corona; Carlos Regalado
Journal:  ScientificWorldJournal       Date:  2014-06-24

9.  Polyphenol-Rich Larix decidua Bark Extract with Antimicrobial Activity against Respiratory-Tract Pathogens: A Novel Bioactive Ingredient with Potential Pharmaceutical and Nutraceutical Applications.

Authors:  Marta Faggian; Giulia Bernabè; Sara Ferrari; Stefano Francescato; Gianni Baratto; Ignazio Castagliuolo; Stefano Dall'Acqua; Gregorio Peron
Journal:  Antibiotics (Basel)       Date:  2021-06-28
  9 in total

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