Literature DB >> 16151160

Biosynthesis of natural flavanones in Saccharomyces cerevisiae.

Yajun Yan1, Abhijeet Kohli, Mattheos A G Koffas.   

Abstract

A four-step flavanone biosynthetic pathway was constructed and introduced into Saccharomyces cerevisiae. The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved.

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Year:  2005        PMID： 16151160      PMCID： PMC1214632          DOI： 10.1128/AEM.71.9.5610-5613.2005

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  16 in total

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Review 6.  The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications.

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Journal:  Microb Cell Fact       Date:  2009-08-13       Impact factor: 5.328
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