Literature DB >> 16148186

Patients with pulmonary tuberculosis develop a strong humoral response against methylated heparin-binding hemagglutinin.

Stefania Zanetti1, Alessandra Bua, Giovanni Delogu, Cinzia Pusceddu, Maristella Mura, Franca Saba, Piero Pirina, Carlo Garzelli, Cono Vertuccio, Leonardo A Sechi, Giovanni Fadda.   

Abstract

Reactivities of human sera against selected recombinant Mycobacterium tuberculosis antigens were assessed by enzyme-linked immunosorbent assay. The results obtained indicate that patients with tuberculosis (TB) do not develop a strong humoral response against PE_PGRS and PPE proteins or against the Ag85B and heparin-binding hemagglutinin (HBHA) recombinant antigens. Conversely, purified methylated HBHA was strongly recognized by sera obtained from TB patients compared to controls.

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Year:  2005        PMID： 16148186      PMCID： PMC1235805          DOI： 10.1128/CDLI.12.9.1135-1138.2005

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  15 in total

Review 1.  The PE multigene family: a 'molecular mantra' for mycobacteria.

Authors:  Michael J Brennan; Giovanni Delogu
Journal:  Trends Microbiol       Date:  2002-05       Impact factor: 17.079

2.  Differential T and B cell responses against Mycobacterium tuberculosis heparin-binding hemagglutinin adhesin in infected healthy individuals and patients with tuberculosis.

Authors:  Chantal Masungi; Stéphane Temmerman; Jean-Paul Van Vooren; Annie Drowart; Kevin Pethe; Franco D Menozzi; Camille Locht; Françoise Mascart
Journal:  J Infect Dis       Date:  2002-01-31       Impact factor: 5.226

3.  The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination.

Authors:  K Pethe; S Alonso; F Biet; G Delogu; M J Brennan; C Locht; F D Menozzi
Journal:  Nature       Date:  2001-07-12       Impact factor: 49.962

4.  Evaluation of BACTEC Mycobacteria Growth Indicator Tube (MGIT 960) automated system for drug susceptibility testing of Mycobacterium tuberculosis.

Authors:  F Ardito; B Posteraro; M Sanguinetti; S Zanetti; G Fadda
Journal:  J Clin Microbiol       Date:  2001-12       Impact factor: 5.948

5.  The use of Ag85 complex as antigen in ELISA for the diagnosis of bovine tuberculosis in dairy cows in Brazil.

Authors:  W Lilenbaum; M C Pessolani; L S Fonseca
Journal:  J Vet Med B Infect Dis Vet Public Health       Date:  2001-04

6.  The role of clinical suspicion in evaluating a new diagnostic test for active tuberculosis: results of a multicenter prospective trial.

Authors:  A Catanzaro; S Perry; J E Clarridge; S Dunbar; S Goodnight-White; P A LoBue; C Peter; G E Pfyffer; M F Sierra; R Weber; G Woods; G Mathews; V Jonas; K Smith; P Della-Latta
Journal:  JAMA       Date:  2000-02-02       Impact factor: 56.272

7.  Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis.

Authors:  G Delogu; M J Brennan
Journal:  Infect Immun       Date:  2001-09       Impact factor: 3.441

Review 8.  Interferon-gamma assays in the immunodiagnosis of tuberculosis: a systematic review.

Authors:  Madhukar Pai; Lee W Riley; John M Colford
Journal:  Lancet Infect Dis       Date:  2004-12       Impact factor: 25.071

9.  Antigens of Mycobacterium tuberculosis expressed during preclinical tuberculosis: serological immunodominance of proteins with repetitive amino acid sequences.

Authors:  K K Singh; X Zhang; A S Patibandla; P Chien; S Laal
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

10.  Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis.

Authors:  Kevin Pethe; Pablo Bifani; Hervé Drobecq; Christian Sergheraert; Anne-Sophie Debrie; Camille Locht; Franco D Menozzi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-29       Impact factor: 11.205
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  9 in total

1.  Assessment of five antigens from Mycobacterium tuberculosis for serodiagnosis of tuberculosis.

Authors:  Xiu-Yun He; Jing Li; Juan Hao; Hong-Bing Chen; Ya-Zhen Zhao; Xiang-Yu Huang; Ke He; Li Xiao; Li-Ping Ye; Yi-Mei Qu; Lin-Hu Ge
Journal:  Clin Vaccine Immunol       Date:  2011-02-02

2.  Mycobacterium tuberculosis HBHA protein reacts strongly with the serum immunoglobulin M of tuberculosis patients.

Authors:  A-Rum Shin; Kil-Soo Lee; Ji-Sook Lee; Su-Young Kim; Chang-Hwa Song; Saet-Byel Jung; Chul-Su Yang; Eun-Kyeong Jo; Jeong-Kyu Park; Tae-Hyun Paik; Hwa-Jung Kim
Journal:  Clin Vaccine Immunol       Date:  2006-08

3.  Methylated HBHA produced in M. smegmatis discriminates between active and non-active tuberculosis disease among RD1-responders.

Authors:  Giovanni Delogu; Teresa Chiacchio; Valentina Vanini; Ornella Butera; Gilda Cuzzi; Alessandra Bua; Paola Molicotti; Stefania Zanetti; Francesco Nicola Lauria; Susanna Grisetti; Nicola Magnavita; Giovanni Fadda; Enrico Girardi; Delia Goletti
Journal:  PLoS One       Date:  2011-03-29       Impact factor: 3.240

4.  Mycobacterial heparin-binding haemagglutinin adhesion-induced interferon & antibody for detection of tuberculosis.

Authors:  Zhaogang Sun; Lihui Nie; Xuxia Zhang; Yan Li; Chuanyou Li
Journal:  Indian J Med Res       Date:  2011-04       Impact factor: 2.375

5.  Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-κB, and MAPK Pathways.

Authors:  Ki-Hye Kim; Chul-Su Yang; A-Rum Shin; So-Ra Jeon; Jeong-Kyu Park; Hwa-Jung Kim; Eun-Kyeong Jo
Journal:  Immune Netw       Date:  2011-04-30       Impact factor: 6.303

Review 6.  Antibodies and tuberculosis.

Authors:  Ashley J Jacobs; Juthathip Mongkolsapaya; Gavin R Screaton; Helen McShane; Robert J Wilkinson
Journal:  Tuberculosis (Edinb)       Date:  2016-08-26       Impact factor: 3.131

7.  Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection.

Authors:  Teresa Chiacchio; Giovanni Delogu; Valentina Vanini; Gilda Cuzzi; Flavio De Maio; Carmela Pinnetti; Alessandro Sampaolesi; Andrea Antinori; Delia Goletti
Journal:  PLoS One       Date:  2017-08-24       Impact factor: 3.240

8.  Pilot study of diagnostic potential of the Mycobacterium tuberculosis recombinant HBHA protein in a vaccinated population in Finland.

Authors:  Laura Savolainen; Liana Pusa; Hwa-Jung Kim; Heidi Sillanpää; Ilkka Seppälä; Tamara Tuuminen
Journal:  PLoS One       Date:  2008-09-25       Impact factor: 3.240

9.  Immunogenicity of heparin-binding hemagglutinin expressed by Pichia pastoris GS115 strain.

Authors:  Xindong Teng; Xiaoguang Chen; Ke Zhu; Hefei Xu
Journal:  Iran J Basic Med Sci       Date:  2018-02       Impact factor: 2.699
  9 in total

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