Literature DB >> 16148182

Endogenous superantigens shape response to exogenous superantigens.

Govindarajan Rajagopalan1, Manisha Singh, Moon M Sen, Narayana S Murali, Karl A Nath, Chella S David.   

Abstract

Endogenous superantigen-mediated thymic negative selection resulted in a paucity of mature T cells bearing T-cell receptor (TCR) Vbeta8 in the periphery. Consequently, the magnitude of immune response to exogenous superantigen staphylococcal enterotoxin B, which activates TCR Vbeta8(+) T cells, was significantly reduced and conferred protection from superantigen-induced mortality.

Mesh：

Substances：

Year:  2005        PMID： 16148182      PMCID： PMC1235787          DOI： 10.1128/CDLI.12.9.1119-1122.2005

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  15 in total

Review 1.  Superantigens: mechanism of T-cell stimulation and role in immune responses.

Authors:  A Herman; J W Kappler; P Marrack; A M Pullen
Journal:  Annu Rev Immunol       Date:  1991       Impact factor: 28.527

Review 2.  The structural basis of T cell activation by superantigens.

Authors:  H Li; A Llera; E L Malchiodi; R A Mariuzza
Journal:  Annu Rev Immunol       Date:  1999       Impact factor: 28.527

3.  Mice lacking all conventional MHC class II genes.

Authors:  L Madsen; N Labrecque; J Engberg; A Dierich; A Svejgaard; C Benoist; D Mathis; L Fugger
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

4.  Negative thymocyte selection to HERV-K18 superantigens in humans.

Authors:  Françoise Meylan; Magda De Smedt; Georges Leclercq; Jean Plum; Olivier Leupin; Samuel Marguerat; Bernard Conrad
Journal:  Blood       Date:  2005-01-11       Impact factor: 22.113

5.  Characterization of HLA DR2 and DQ8 transgenic mouse with a new engineered mouse class II deletion, which lacks all endogenous class II genes.

Authors:  S Cheng; M Smart; J Hanson; C S David
Journal:  J Autoimmun       Date:  2003-11       Impact factor: 7.094

6.  Human CD4 and human major histocompatibility complex class II (DQ6) transgenic mice: supersensitivity to superantigen-induced septic shock.

Authors:  R S Yeung; J M Penninger; T Kündig; W Khoo; P S Ohashi; G Kroemer; T W Mak
Journal:  Eur J Immunol       Date:  1996-05       Impact factor: 5.532

Review 7.  Human endogenous retroviruses: transposable elements with potential?

Authors:  P N Nelson; P Hooley; D Roden; H Davari Ejtehadi; P Rylance; P Warren; J Martin; P G Murray
Journal:  Clin Exp Immunol       Date:  2004-10       Impact factor: 4.330

8.  Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines.

Authors:  Luis DaSilva; Brent C Welcher; Robert G Ulrich; M Javad Aman; Chella S David; Sina Bavari
Journal:  J Infect Dis       Date:  2002-05-23       Impact factor: 5.226

Review 9.  Thymic repertoire selection by superantigens: presentation by human and mouse MHC molecules.

Authors:  E Simpson; K Takacs; D M Altmann
Journal:  Thymus       Date:  1994

10.  A role for Fas in negative selection of thymocytes in vivo.

Authors:  H Kishimoto; C D Surh; J Sprent
Journal:  J Exp Med       Date:  1998-05-04       Impact factor: 14.307
View more
  5 in total

1.  Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B.

Authors:  Govindarajan Rajagopalan; Michele K Smart; Robin Patel; Chella S David
Journal:  Infect Immun       Date:  2006-10       Impact factor: 3.441

2.  Early gene expression changes induced by the bacterial superantigen staphylococcal enterotoxin B and its modulation by a proteasome inhibitor.

Authors:  Govindarajan Rajagopalan; Ashenafi Y Tilahun; Yan W Asmann; Chella S David
Journal:  Physiol Genomics       Date:  2009-03-31       Impact factor: 3.107

3.  Superantigens produced by catheter-associated Staphylococcus aureus elicit systemic inflammatory disease in the absence of bacteremia.

Authors:  Jin-Won Chung; Kerryl E Greenwood-Quaintance; Melissa J Karau; Ashenafi Tilahun; Shahryar Rostamkolaei Khaleghi; Vaidehi R Chowdhary; Chella S David; Robin Patel; Govindarajan Rajagopalan
Journal:  J Leukoc Biol       Date:  2015-05-15       Impact factor: 4.962

4.  Modulation of Immune response by Ultra-violet light in HLA class-II transgenic mice.

Authors:  Daniel Bastardo Blanco; David Luckey; Michele Smart; Mark Pittelkow; Rajiv Kumar; Chella S David; Ashutosh K Mangalam
Journal:  Jacobs J Allergy Immunol       Date:  2014-12

5.  Interferon gamma-dependent intestinal pathology contributes to the lethality in bacterial superantigen-induced toxic shock syndrome.

Authors:  Ashenafi Y Tilahun; Marah Holz; Tsung-Teh Wu; Chella S David; Govindarajan Rajagopalan
Journal:  PLoS One       Date:  2011-02-03       Impact factor: 3.240
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.