Literature DB >> 16988282

Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B.

Govindarajan Rajagopalan1, Michele K Smart, Robin Patel, Chella S David.   

Abstract

Conjunctival exposure to the Staphylococcus aureus superantigen staphylococcal enterotoxin B (SEB) may occur accidentally, as a result of bioterrorism, or during colonization or infection of the external eye. Using human leukocyte antigen class II transgenic mice, we show for the first time that conjunctival exposure to SEB can cause robust systemic immune activation.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16988282      PMCID： PMC1594882          DOI： 10.1128/IAI.00671-06

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  38 in total

Review 1.  Toxins as weapons of mass destruction. A comparison and contrast with biological-warfare and chemical-warfare agents.

Authors:  J M Madsen
Journal:  Clin Lab Med       Date:  2001-09       Impact factor: 1.935

2.  A high incidence of Staphylococcus aureus colonization in the external eyes of patients with atopic dermatitis.

Authors:  K Nakata; Y Inoue; J Harada; N Maeda; H Watanabe; Y Tano; Y Shimomura; S Harino; M Sawa
Journal:  Ophthalmology       Date:  2000-12       Impact factor: 12.079

3.  Ocular infections in patients with atopic dermatitis.

Authors:  Yoshitsugu Inoue
Journal:  Int Ophthalmol Clin       Date:  2002

4.  Methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative Staphylococcus ocular surface infection efficacy of chloramphenicol eye drops.

Authors:  Masahiko Fukuda; Hideyuki Ohashi; Chota Matsumoto; Soichiro Mishima; Yoshikazu Shimomura
Journal:  Cornea       Date:  2002-10       Impact factor: 2.651

Review 5.  Infectious keratitis after photorefractive keratectomy.

Authors:  Eric D Donnenfeld; Terrence P O'Brien; Renée Solomon; Henry D Perry; Mark G Speaker; John Wittpenn
Journal:  Ophthalmology       Date:  2003-04       Impact factor: 12.079

6.  Correlation of body temperature with protection against staphylococcal enterotoxin B exposure and use in determining vaccine dose-schedule.

Authors:  James W Boles; M Louise M Pitt; Ross D LeClaire; Paul H Gibbs; Robert G Ulrich; Sina Bavari
Journal:  Vaccine       Date:  2003-06-20       Impact factor: 3.641

7.  Corneal virulence of Staphylococcus aureus in an experimental model of keratitis.

Authors:  Joseph J Dajcs; Brett A Thibodeaux; Dalia O Girgis; Richard J O'Callaghan
Journal:  DNA Cell Biol       Date:  2002 May-Jun       Impact factor: 3.311

8.  Staphylococcal enterotoxin B-induced activation and concomitant resistance to cell death in CD28-deficient HLA-DQ8 transgenic mice.

Authors:  Govindarajan Rajagopalan; Michele K Smart; Eric V Marietta; Chella S David
Journal:  Int Immunol       Date:  2002-07       Impact factor: 4.823

9.  Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines.

Authors:  Luis DaSilva; Brent C Welcher; Robert G Ulrich; M Javad Aman; Chella S David; Sina Bavari
Journal:  J Infect Dis       Date:  2002-05-23       Impact factor: 5.226

10.  A new topical model of Staphylococcus corneal infection in the mouse.

Authors:  Dalia O Girgis; Gregory D Sloop; Julian M Reed; Richard J O'Callaghan
Journal:  Invest Ophthalmol Vis Sci       Date:  2003-04       Impact factor: 4.799
View more
  6 in total

1.  Early gene expression changes induced by the bacterial superantigen staphylococcal enterotoxin B and its modulation by a proteasome inhibitor.

Authors:  Govindarajan Rajagopalan; Ashenafi Y Tilahun; Yan W Asmann; Chella S David
Journal:  Physiol Genomics       Date:  2009-03-31       Impact factor: 3.107

Review 2.  Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome.

Authors:  Amanda J Brosnahan; Patrick M Schlievert
Journal:  FEBS J       Date:  2011-05-19       Impact factor: 5.542

3.  Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

Authors:  Anthony B Nesburn; Ilham Bettahi; Gargi Dasgupta; Alami Aziz Chentoufi; Xiuli Zhang; Sylvaine You; Naoyuki Morishige; Andrew J Wahlert; Donald J Brown; James V Jester; Steven L Wechsler; Lbachir BenMohamed
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

4.  Cytolysins augment superantigen penetration of stratified mucosa.

Authors:  Amanda J Brosnahan; Mary J Mantz; Christopher A Squier; Marnie L Peterson; Patrick M Schlievert
Journal:  J Immunol       Date:  2009-02-15       Impact factor: 5.422

5.  Chronic exposure to staphylococcal superantigen elicits a systemic inflammatory disease mimicking lupus.

Authors:  Vaidehi R Chowdhary; Ashenafi Y Tilahun; Chad R Clark; Joseph P Grande; Govindarajan Rajagopalan
Journal:  J Immunol       Date:  2012-07-13       Impact factor: 5.422

6.  Interferon gamma-dependent intestinal pathology contributes to the lethality in bacterial superantigen-induced toxic shock syndrome.

Authors:  Ashenafi Y Tilahun; Marah Holz; Tsung-Teh Wu; Chella S David; Govindarajan Rajagopalan
Journal:  PLoS One       Date:  2011-02-03       Impact factor: 3.240
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.