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Literature DB >> 16142931

Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers.

Almut Mecke¹, Dong-Kuk Lee, Ayyalusamy Ramamoorthy, Bradford G Orr, Mark M Banaszak Holl.

Abstract

Polycationic polymers are known to disrupt lipid bilayers. In this letter, we report the dependence of this disruption on the lipid structural phase. DMPC bilayers are exposed to two polycationic polymeric nanoparticles, PAMAM dendrimers and MSI-78. We find that regions of the bilayer that are in the gel phase are unaffected by the presence of polymers, whereas the liquid phase is disrupted.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16142931 PMCID： PMC1440293 DOI： 10.1021/la051800w

Source DB: PubMed Journal: Langmuir ISSN： 0743-7463 Impact factor: 3.882

23 in total

1. Studies on the internalization mechanism of cationic cell-penetrating peptides.

Authors: Guillaume Drin; Sylvine Cottin; Emmanuelle Blanc; Anthony R Rees; Jamal Temsamani
Journal: J Biol Chem Date: 2003-06-03 Impact factor: 5.157

2. A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides.

Authors: Rainer Fischer; Karsten Köhler; Mariola Fotin-Mleczek; Roland Brock
Journal: J Biol Chem Date: 2004-01-05 Impact factor: 5.157

Review 3. Cell penetrating peptides in drug delivery.

Authors: Eric L Snyder; Steven F Dowdy
Journal: Pharm Res Date: 2004-03 Impact factor: 4.200

4. Lipid membrane phase behaviour elucidated in real time by controlled environment atomic force microscopy.

Authors: Fuyuki Tokumasu; Albert J Jin; James A Dvorak
Journal: J Electron Microsc (Tokyo) Date: 2002

5. Membrane interaction and cellular internalization of penetratin peptides.

Authors: Bart Christiaens; Johan Grooten; Michael Reusens; Alain Joliot; Marc Goethals; Joël Vandekerckhove; Alain Prochiantz; Maryvonne Rosseneu
Journal: Eur J Biochem Date: 2004-03

6. Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin.

Authors: M J Janiak; D M Small; G G Shipley
Journal: J Biol Chem Date: 1979-07-10 Impact factor: 5.157

7. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport.

Authors: Seungpyo Hong; Anna U Bielinska; Almut Mecke; Balazs Keszler; James L Beals; Xiangyang Shi; Lajos Balogh; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal: Bioconjug Chem Date: 2004 Jul-Aug Impact factor: 4.774

8. Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37.

Authors: Katherine A Henzler-Wildman; Gary V Martinez; Michael F Brown; A Ramamoorthy
Journal: Biochemistry Date: 2004-07-06 Impact factor: 3.162

9. Structure and mechanical properties of giant lipid (DMPC) vesicle bilayers from 20 degrees C below to 10 degrees C above the liquid crystal-crystalline phase transition at 24 degrees C.

Authors: D Needham; E Evans
Journal: Biochemistry Date: 1988-10-18 Impact factor: 3.162

10. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis.

Authors: Dagmar Fischer; Youxin Li; Barbara Ahlemeyer; Josef Krieglstein; Thomas Kissel
Journal: Biomaterials Date: 2003-03 Impact factor: 12.479

21 in total

1. Characterization of the structure and membrane interaction of the antimicrobial peptides aurein 2.2 and 2.3 from Australian southern bell frogs.

Authors: Yeang-Ling Pan; John T-J Cheng; John Hale; Jinhe Pan; Robert E W Hancock; Suzana K Straus
Journal: Biophys J Date: 2007-01-26 Impact factor: 4.033

Review 2. Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face?

Authors: Pascale R Leroueil; Seungpyo Hong; Almut Mecke; James R Baker; Bradford G Orr; Mark M Banaszak Holl
Journal: Acc Chem Res Date: 2007-05-03 Impact factor: 22.384

3. Poly-L-lysine-induced morphology changes in mixed anionic/zwitterionic and neat zwitterionic-supported phospholipid bilayers.

Authors: Tighe A Spurlin; Andrew A Gewirth
Journal: Biophys J Date: 2006-07-28 Impact factor: 4.033

Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers.

1. Studies on the internalization mechanism of cationic cell-penetrating peptides.

2. A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides.

Review 3. Cell penetrating peptides in drug delivery.

4. Lipid membrane phase behaviour elucidated in real time by controlled environment atomic force microscopy.

5. Membrane interaction and cellular internalization of penetratin peptides.

6. Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin.

7. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport.

8. Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37.

9. Structure and mechanical properties of giant lipid (DMPC) vesicle bilayers from 20 degrees C below to 10 degrees C above the liquid crystal-crystalline phase transition at 24 degrees C.

10. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis.

1. Characterization of the structure and membrane interaction of the antimicrobial peptides aurein 2.2 and 2.3 from Australian southern bell frogs.

Review 2. Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face?

3. Poly-L-lysine-induced morphology changes in mixed anionic/zwitterionic and neat zwitterionic-supported phospholipid bilayers.

Review 4. Chemical basis of interactions between engineered nanoparticles and biological systems.

5. Surface interaction and behavior of poly(amidoamine) dendrimers: deformability and lipid bilayer disruption.

6. Interactions of poly(amidoamine) dendrimers with Survanta lung surfactant: the importance of lipid domains.

Review 7. Beyond NMR spectra of antimicrobial peptides: dynamical images at atomic resolution and functional insights.

8. Poly(amidoamine) dendrimers on lipid bilayers II: Effects of bilayer phase and dendrimer termination.

9. Stoichiometry and Structure of Poly(amidoamine) Dendrimer-Lipid Complexes.

10. Antibacterial activities of poly(amidoamine) dendrimers terminated with amino and poly(ethylene glycol) groups.