Literature DB >> 16141587

New plastoquinones isolated from the brown alga, Sargassum micracanthum.

Jun Mori1, Makoto Iwashima, Hiroko Wakasugi, Haruo Saito, Takayuki Matsunaga, Masaru Ogasawara, Satoshi Takahashi, Hideyo Suzuki, Toshimitsu Hayashi.   

Abstract

Four new plastoquinones were isolated from the methanolic extract of the brown alga, Sargassum micracanthum. Their structures were elucidated based on spectroscopic analysis and chemical conversions from 2-geranylgeranyl-6-methyl-1,4-benzohydroquinone. These plastoquinones exhibited significant antioxidant activities such as an inhibitory effect on lipid peroxidation and a radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH). Some of the new plastoquiones showed cytotoxic activity against cancer cell line.

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Year:  2005        PMID: 16141587     DOI: 10.1248/cpb.53.1159

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  11 in total

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