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Literature DB >> 16132290

Use of dexmedetomidine in a pediatric heart transplant patient.

Abstract

Dexmedetomidine is a new sedative and analgesic agent that has a unique property of lack of respiratory depression. We describe a pediatric case in which the use of dexmedetomidine enabled us to successfully extubate a 12-year-old heart transplant patient with acute pneumonia after several failed attempts with the use of more conventional sedation.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2005 PMID： 16132290 DOI： 10.1007/s00246-005-0683-3

Source DB: PubMed Journal: Pediatr Cardiol ISSN： 0172-0643 Impact factor: 1.655

23 in total

Review 1. Complications of sedation with midazolam in the intensive care unit and a comparison with other sedative regimens.

Authors: A Shafer
Journal: Crit Care Med Date: 1998-05 Impact factor: 7.598

Review 2. Medetomidine--a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects.

Authors: H Scheinin; R Virtanen; E MacDonald; R Lammintausta; M Scheinin
Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 1989 Impact factor: 5.067

3. Sedation in intensive care--a postal survey.

Authors: J F Bion; I M Ledingham
Journal: Intensive Care Med Date: 1987 Impact factor: 17.440

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Authors: K L Kong; S M Willatts; C Prys-Roberts
Journal: BMJ Date: 1989-05-13

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Authors: M H Kollef; N T Levy; T S Ahrens; R Schaiff; D Prentice; G Sherman
Journal: Chest Date: 1998-08 Impact factor: 9.410

Review 6. The use of sedative agents in critically ill patients.

Authors: A M Burns; M P Shelly; G R Park
Journal: Drugs Date: 1992-04 Impact factor: 9.546

Review 7. Optimal intravenous dosing strategies for sedatives and analgesics in the intensive care unit.

Authors: J Barr; A Donner
Journal: Crit Care Clin Date: 1995-10 Impact factor: 3.598

Review 8. Complications associated with sedative and neuromuscular blocking drugs in critically ill patients.

Authors: R C Prielipp; D B Coursin; K E Wood; M J Murray
Journal: Crit Care Clin Date: 1995-10 Impact factor: 3.598

9. Haemodynamic responses to extubation after cardiac surgery with and without continued sedation.

Authors: J Conti; D Smith
Journal: Br J Anaesth Date: 1998-06 Impact factor: 9.166

10. Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate.

Authors: J P Belleville; D S Ward; B C Bloor; M Maze
Journal: Anesthesiology Date: 1992-12 Impact factor: 7.892

8 in total

1. Dexmedetomidine for transport of a spontaneously breathing combative child.

Authors: Kevin M Watt; Jason Walgos; Ira M Cheifetz; David A Turner
Journal: Pediatrics Date: 2012-08-13 Impact factor: 7.124

2. Evaluation of adverse events noted in children receiving continuous infusions of dexmedetomidine in the intensive care unit.

Authors: Brooke L Honey; Donald L Harrison; Andrew K Gormley; Peter N Johnson
Journal: J Pediatr Pharmacol Ther Date: 2010-01

Use of dexmedetomidine in a pediatric heart transplant patient.

Review 1. Complications of sedation with midazolam in the intensive care unit and a comparison with other sedative regimens.

Review 2. Medetomidine--a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects.

3. Sedation in intensive care--a postal survey.

4. Isoflurane compared with midazolam for sedation in the intensive care unit.

5. The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation.

Review 6. The use of sedative agents in critically ill patients.

Review 7. Optimal intravenous dosing strategies for sedatives and analgesics in the intensive care unit.

Review 8. Complications associated with sedative and neuromuscular blocking drugs in critically ill patients.

9. Haemodynamic responses to extubation after cardiac surgery with and without continued sedation.

10. Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate.

1. Dexmedetomidine for transport of a spontaneously breathing combative child.

2. Evaluation of adverse events noted in children receiving continuous infusions of dexmedetomidine in the intensive care unit.

Review 3. Dexmedetomidine: applications for the pediatric patient with congenital heart disease.

4. Hemodynamic effects of dexmedetomidine in critically ill neonates and infants with heart disease.

Review 5. Clinical uses of dexmedetomidine in pediatric patients.

6. Dexmedetomidine Use in Critically Ill Children With Acute Respiratory Failure.

7. High-dose dexmedetomidine-induced hypertension in a child with traumatic brain injury.

8. Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in rats.