Literature DB >> 22891226

Dexmedetomidine for transport of a spontaneously breathing combative child.

Kevin M Watt1, Jason Walgos, Ira M Cheifetz, David A Turner.   

Abstract

Interhospital transport presents a challenge for pediatricians, and airway protection is often a significant concern. The severely agitated child without respiratory compromise poses an extremely difficult dilemma, as most sedative agents can cause respiratory depression. Intubation offers definitive control of the airway but is not without risk, especially in an environment where experience and resources for pediatric intubation may be limited. Dexmedetomidine may be used for sedation in certain circumstances for the transport of a child without the need for intubation and mechanical ventilation.

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Year:  2012        PMID: 22891226      PMCID: PMC3428757          DOI: 10.1542/peds.2011-3397

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  30 in total

1.  Excess morbidity associated with interhospital transport.

Authors:  R K Kanter; N M Boeing; W P Hannan; D L Kanter
Journal:  Pediatrics       Date:  1992-12       Impact factor: 7.124

2.  Dexmedetomidine and cardiac arrest.

Authors:  Esperanza Ingersoll-Weng; Gerard R Manecke; Patricia A Thistlethwaite
Journal:  Anesthesiology       Date:  2004-03       Impact factor: 7.892

3.  Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial.

Authors:  M Gausche; R J Lewis; S J Stratton; B E Haynes; C S Gunter; S M Goodrich; P D Poore; M D McCollough; D P Henderson; F D Pratt; J S Seidel
Journal:  JAMA       Date:  2000-02-09       Impact factor: 56.272

4.  Central alpha 2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine.

Authors:  J M Savola; R Virtanen
Journal:  Eur J Pharmacol       Date:  1991-03-26       Impact factor: 4.432

5.  The use of vasoactive agents via peripheral intravenous access during transport of critically III infants and children.

Authors:  David A Turner; Monica E Kleinman
Journal:  Pediatr Emerg Care       Date:  2010-08       Impact factor: 1.454

6.  The effects of increasing plasma concentrations of dexmedetomidine in humans.

Authors:  T J Ebert; J E Hall; J A Barney; T D Uhrich; M D Colinco
Journal:  Anesthesiology       Date:  2000-08       Impact factor: 7.892

7.  Synergistic interaction between alpha 2-adrenergic agonists and benzodiazepines in rats.

Authors:  M Salonen; K Reid; M Maze
Journal:  Anesthesiology       Date:  1992-06       Impact factor: 7.892

Review 8.  Endotracheal intubations in rural pediatric trauma patients.

Authors:  P F Ehrlich; P S Seidman; O Atallah; A Haque; J Helmkamp
Journal:  J Pediatr Surg       Date:  2004-09       Impact factor: 2.545

9.  Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam.

Authors:  Joseph D Tobias; John W Berkenbosch
Journal:  South Med J       Date:  2004-05       Impact factor: 0.954

10.  Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children.

Authors:  Mauricio E Ibacache; Hernán R Muñoz; Verena Brandes; Anita L Morales
Journal:  Anesth Analg       Date:  2004-01       Impact factor: 5.108

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  2 in total

1.  Dexmedetomidine Infusion to Control Agitation due to Anticholinergic Toxidromes in Adolescents, a Case Series.

Authors:  Samantha W Gee; Ada Lin; Joseph D Tobias
Journal:  J Pediatr Pharmacol Ther       Date:  2015 Jul-Aug

2.  Dexmedetomidine compared with propofol for pediatric sedation during cerebral angiography.

Authors:  Ke Peng; Jian Li; Fu-Hai Ji; Zhi Li
Journal:  J Res Med Sci       Date:  2014-06       Impact factor: 1.852

  2 in total

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