Literature DB >> 16125942

Autologous osteochondral transplantation for the treatment of chondral defects of the knee.

D Karataglis1, M A Green, D J A Learmonth.   

Abstract

Full-thickness chondral defects of weight-bearing articular surfaces of the knee are a difficult condition to treat. Our aim is to evaluate the mid- and long-term functional outcome of the treatment of osteochondral defects of the knee with autologous osteochondral transplantation with the OATS technique. Thirty-six patients (37 procedures) were included in this study. Twenty-three patients were male and thirteen were female with a mean age of 31.9 years (range: 18-48 years). The cause of the defect was OCD in 10 cases, AVN in 2, lateral patellar maltracking in 7, while in the remaining 17 patients the defect was post-traumatic. The lesion was located on the femoral condyles in 26 cases and the patellofemoral joint in the remaining 11. The average area covered was 2.73 cm(2) (range: 0.8-12 cm(2)) and patients were followed for an average of 36.9 months (range: 18-73 months). The average score in their Tegner Activity Scale was 3.76 (range: 1-8), while their score in Activities of Daily Living Scale of the Knee Outcome Survey ranged from 18 to 98 with an average of 72.3. Thirty-two out of 37 patients (86.5%) reported improvement of their pre-operative symptoms. All but 5 patients returned to their previous occupation while 18 went back to sports. No correlation was found between patient age at operation, the size or site of the chondral lesion and the functional outcome. We believe that autologous osteochondral grafting with the OATS technique is a safe and successful treatment option for focal osteochondral defects of the knee. It offers a very satisfactory functional outcome and does not compromise the patient's future options.

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Mesh:

Year:  2005        PMID: 16125942     DOI: 10.1016/j.knee.2005.05.006

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  17 in total

Review 1.  [Repair of local cartilage defects in the patellofemoral joint].

Authors:  S Anders; P Lechler; J Grifka; J Schaumburger
Journal:  Orthopade       Date:  2011-10       Impact factor: 1.087

2.  Case report: Osteochondritis dissecans in twins: treatment with fresh osteochondral grafts.

Authors:  Timothy Mackie; Ross M Wilkins
Journal:  Clin Orthop Relat Res       Date:  2009-08-07       Impact factor: 4.176

Review 3.  We do not have evidence based methods for the treatment of cartilage defects in the knee.

Authors:  Jan P Benthien; Manuela Schwaninger; Peter Behrens
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-11-18       Impact factor: 4.342

4.  Bone scintigraphy after osteochondral autograft transplantation in the knee: 13 patients followed for 4 years.

Authors:  Niels B Kock; Esther van Tankeren; Wim J G Oyen; Ate B Wymenga; Job L C van Susante
Journal:  Acta Orthop       Date:  2010-04-06       Impact factor: 3.717

5.  Is There a Connection Between Attention Deficit Hyperactivity Disorder and Osteochondritis Dissecans?

Authors:  Kevin M Dale; Andrew Livermore; Rewais Hanna; Susan Laham; Kenneth J Noonan; Matthew Haleanski; Pamela J Long
Journal:  Iowa Orthop J       Date:  2020

6.  Does operative fixation of an osteochondritis dissecans loose body result in healing and long-term maintenance of knee function?

Authors:  Robert A Magnussen; James L Carey; Kurt P Spindler
Journal:  Am J Sports Med       Date:  2009-02-09       Impact factor: 6.202

7.  In vitro isolation and cultivation of human chondrocytes for osteoarthritis renovation.

Authors:  Jiaming Xu; Changqing Zhang
Journal:  In Vitro Cell Dev Biol Anim       Date:  2014-06-11       Impact factor: 2.416

8.  Chondrocyte survival in osteochondral transplant cylinders depends on the harvesting technique.

Authors:  Benedikt Hafke; Maximilian Petri; Eduardo Suero; Claudia Neunaber; Sebastian Kwisda; Christian Krettek; Michael Jagodzinski; Mohamed Omar
Journal:  Int Orthop       Date:  2015-12-11       Impact factor: 3.075

9.  Early determinants of long-term clinical outcome after cartilage repair surgery in the knee.

Authors:  Eirik Solheim; Janne Hegna; Eivind Inderhaug
Journal:  J Orthop       Date:  2018-01-31

10.  Trapezoidal osteochondral autologous plug single-block graft for treating chondral lesions of the knee: clinical and functional medium-term results in an observational study.

Authors:  Cezar Teruyuki Kawano; Márcio Moura Rocha dos Santos; Marcus Guilherme de Oliveira; Tadeu Colens Ourivio
Journal:  Clinics (Sao Paulo)       Date:  2012-10       Impact factor: 2.365

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