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Literature DB >> 1612363

Expression of an elongation factor 1 gamma-related sequence in adenocarcinomas of the colon.

Abstract

The authors have previously reported that a messenger RNA (mRNA) bearing 60% homology to elongation factor 1 gamma in Artemia salina was overexpressed in 7 of 9 pancreatic tumors relative to normal appearing adjacent tissue. The purpose of the present study was to determine if this pattern of overexpression is also detected in colorectal carcinoma. Overexpression was observed in 25 of 29 colorectal carcinomas, relative to normal adjacent tissue. Of them, mRNA was overexpressed in 2 tumors classified as Dukes' D, in 8 of 11 tumors classified as Dukes' B2, and in 15 of 16 tumors classified as Dukes' C2.

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Year: 1992 PMID： 1612363 DOI： 10.1016/0016-5085(92)91101-9

Source DB: PubMed Journal: Gastroenterology ISSN： 0016-5085 Impact factor: 22.682

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Cited

14 in total

1. Elongation factor-1 messenger-RNA levels in cultured cells are high compared to tissue and are not drastically affected further by oncogenic transformation.

Authors: J Sanders; J A Maassen; W Möller
Journal: Nucleic Acids Res Date: 1992-11-25 Impact factor: 16.971

2. Up-regulation of expression of translation factors--a novel molecular mechanism for cadmium carcinogenesis.

Authors: Pius Joseph; Yi-Xiong Lei; Tong-man Ong
Journal: Mol Cell Biochem Date: 2004-01 Impact factor: 3.396

3. Energetics of Glutathione Binding to Human Eukaryotic Elongation Factor 1 Gamma: Isothermal Titration Calorimetry and Molecular Dynamics Studies.

Authors: Thabiso N Tshabalala; Mihai-Silviu Tomescu; Allan Prior; Vijayakumar Balakrishnan; Yasien Sayed; Heini W Dirr; Ikechukwu Achilonu
Journal: Protein J Date: 2016-12 Impact factor: 2.371

4. Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.

Authors: R Shen; Z Z Su; C A Olsson; P B Fisher
Journal: Proc Natl Acad Sci U S A Date: 1995-07-18 Impact factor: 11.205

5. Purification of total RNA from human stool samples.

Authors: R J Alexander; R F Raicht
Journal: Dig Dis Sci Date: 1998-12 Impact factor: 3.199

6. 1H, 15N and 13C resonance assignments of the highly conserved 19 kDa C-terminal domain from human elongation factor 1Bgamma.

Authors: Sophie Vanwetswinkel; Jan Kriek; Gregers R Andersen; Jan Dijk; Gregg Siegal
Journal: J Biomol NMR Date: 2003-06 Impact factor: 2.835

Expression of an elongation factor 1 gamma-related sequence in adenocarcinomas of the colon.

1. Elongation factor-1 messenger-RNA levels in cultured cells are high compared to tissue and are not drastically affected further by oncogenic transformation.

2. Up-regulation of expression of translation factors--a novel molecular mechanism for cadmium carcinogenesis.

3. Energetics of Glutathione Binding to Human Eukaryotic Elongation Factor 1 Gamma: Isothermal Titration Calorimetry and Molecular Dynamics Studies.

4. Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.

5. Purification of total RNA from human stool samples.

6. 1H, 15N and 13C resonance assignments of the highly conserved 19 kDa C-terminal domain from human elongation factor 1Bgamma.

Review 7. Functional and pathologic association of aminoacyl-tRNA synthetases with cancer.

8. Identification of a 170-kDa protein over-expressed in lung cancers.

9. Blood translation elongation factor-1δ is a novel marker for cadmium exposure.

10. Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma.