Literature DB >> 16121692

SPK-843 (Aparts/Kaken).

Noer Kasanah1, Mark T Hamann.   

Abstract

SPK-843 is a water-soluble antibiotic under co-development by Aparts and Kaken for the potential treatment of systemic fungal infections. By November 2004, SPK-843 was in phase II trials for systemic mycosis.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16121692      PMCID： PMC4928195     

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN： 1472-4472


  20 in total

Review 1.  The 1998 Garrod lecture. Current and future antifungal therapy: new targets for antifungal agents.

Authors:  V T Andriole
Journal:  J Antimicrob Chemother       Date:  1999-08       Impact factor: 5.790

2.  The use of lipid emulsions for the i.v. administration of a new water soluble polyene antibiotic, SPK-843.

Authors:  G Mozzi; P Benelli; T Bruzzese; M R Galmozzi; A Bonabello
Journal:  J Antimicrob Chemother       Date:  2002-02       Impact factor: 5.790

Review 3.  Antifungal antibiotics.

Authors:  M Gupte; P Kulkarni; B N Ganguli
Journal:  Appl Microbiol Biotechnol       Date:  2002-01       Impact factor: 4.813

4.  In vitro activity of a new polyene SPK-843 against Candida spp, Cryptococcus neoformans and Aspergillus spp clinical isolates.

Authors:  A S Kantarcioglu; A Yucel; V Vidotto
Journal:  J Chemother       Date:  2003-06       Impact factor: 1.714

Review 5.  The role of caspofungin and the echinocandins in the antifungal armamentarium.

Authors:  Vicki A Morrison
Journal:  Curr Opin Investig Drugs       Date:  2002-10

6.  Potent antifungal effects of a new derivative of partricin A in a murine model of cerebral cryptococcosis.

Authors:  T Luna; R Mazzolla; G Romanò; E Blasi
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

7.  Pharmacokinetics in rats of n-dimethylaminoacetyl-partricin a 2-dimethylaminoethylamide diascorbate (spk-843).

Authors:  T Bruzzese; M R Galmozzi; G Buffa; P Sala; A Bonabello
Journal:  Chemotherapy       Date:  2001 Mar-Apr       Impact factor: 2.544

8.  Pharmacokinetics of a new derivative of partricin A (SPA-S-753) in rodents.

Authors:  M R Galmozzi; T Bruzzese; G Buffa; A Bonabello
Journal:  Chemotherapy       Date:  2000 May-Jun       Impact factor: 2.544

Review 9.  Microbial natural products as a source of antifungals.

Authors:  M F Vicente; A Basilio; A Cabello; F Peláez
Journal:  Clin Microbiol Infect       Date:  2003-01       Impact factor: 8.067

10.  Characterization of the antifungal and antiprotozoal antibiotic partricin and structural studies on partricins A and B.

Authors:  R C Tweit; R C Pandey; K L Rinehart
Journal:  J Antibiot (Tokyo)       Date:  1982-08       Impact factor: 2.649
View more
  1 in total

1.  Metabolism and resistance of Fusarium spp. to the manzamine alkaloids via a putative retro pictet-spengler reaction and utility of the rational design of antimalarial and antifungal agents.

Authors:  Noer Kasanah; Lorelei Lucas Farr; Abbas Gholipour; David E Wedge; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2014-02-20       Impact factor: 3.619
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.