Literature DB >> 16119964

Shortcut to fmoc-protected phosphinic pseudodipeptidic blocks.

Magdalini Matziari1, Athanasios Yiotakis.   

Abstract

A three-component condensation reaction of Fmoc-carbamate, aldehydes, and alkylphosphinic acids provides a new, direct, and efficient method for synthesizing Fmoc-protected phosphinic pseudodipeptidic blocks, directly usable for solid-phase peptide synthesis. [reaction: see text]

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Year:  2005        PMID： 16119964     DOI： 10.1021/ol051622y

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors.

Authors:  Janelle Lauer-Fields; Keith Brew; John K Whitehead; Shunzi Li; Robert P Hammer; Gregg B Fields
Journal:  J Am Chem Soc       Date:  2007-08-02       Impact factor: 15.419

2.  Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions.

Authors:  Moaz M Abdou; Paul M O'Neill; Eric Amigues; Magdalini Matziari
Journal:  ACS Omega       Date:  2022-06-16

3.  Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.

Authors:  Stamatia Vassiliou; Ewelina Węglarz-Tomczak; Łukasz Berlicki; Małgorzata Pawełczak; Bogusław Nocek; Rory Mulligan; Andrzej Joachimiak; Artur Mucha
Journal:  J Med Chem       Date:  2014-09-22       Impact factor: 7.446

4.  Functional examination of novel kisspeptin phosphinic peptides.

Authors:  Xiaoyang Zhang; Magdalini Matziari; Yixin Xie; David Fernig; Rong Rong; Jia Meng; Zhi-Liang Lu
Journal:  PLoS One       Date:  2018-04-03       Impact factor: 3.240

Review 5.  Synthesis and modifications of phosphinic dipeptide analogues.

Authors:  Artur Mucha
Journal:  Molecules       Date:  2012-11-15       Impact factor: 4.411
  5 in total

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