| Literature DB >> 16119944 |
Jone Iriondo-Alberdi1, Jesus E Perea-Buceta, Michael F Greaney.
Abstract
A six-step approach to the tetracyclic core of merrilactone A is described that uses an intramolecular Paterno-Büchi photoaddition to install the key oxetane ring. Irradiation of bicyclic enone 16, constructed through cyclopentenone alkylation followed by a domino oxy-/carbopalladation reaction, produces the tetracyclic oxetane 17 in excellent yield, having the core carbon skeleton of the target compound merrilactone A. [reaction: see text]Entities:
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Year: 2005 PMID： 16119944 DOI： 10.1021/ol0514496
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005