Literature DB >> 16118092

Prostate-specific antigen testing in general practice: a survey among 325 general practitioners in Denmark.

Morten Jønler1, Ben Eddy, Johan Poulsen.   

Abstract

OBJECTIVES: Prostate-specific antigen (PSA) is a well-known and -utilized tumor marker for prostate cancer. Elevated PSA values are not specific for prostate cancer as they may be caused by other benign conditions. PSA testing is widely used by urologists and non-urologists. Interpretation of test results is difficult but important. Referral of patients for further work-up on suspicion of prostate diseases is mainly done by general practitioners (GPs). As the GP remains the gatekeeper between the patient and the urologist in terms of diagnosing prostate diseases, basic knowledge of PSA testing is crucial. The purpose of this study was to evaluate the basic use and knowledge of PSA testing and to give an estimate of the need for further education in PSA testing amongst GPs in our area.
MATERIAL AND METHODS: A questionnaire regarding PSA testing and associated needs for education was mailed to all GPs in the Northern County of Denmark. Non-respondents were contacted by mail.
RESULTS: Of the contacted GPs, 90% responded. Only 28% of GPs measured PSA in all males complaining of lower urinary tract symptoms (LUTS). Of patients seen as part of a general health check-up, PSA testing was done in 10%. The median PSA value for referral to urologists for further work-up was 5 ng/ml, but the decision was influenced by PSA value (79%), age (65%) and findings on digital rectal examination (DRE) (87%). Opportunistic screening for prostate cancer was done by 14% of GPs. Of the GPs who responded, 24% stated that they did not need any further education regarding PSA testing.
CONCLUSIONS: The results of this study demonstrate that PSA testing is not standardized in our area. GPs do not test patients on the basis of recommendations provided by national or international societies. PSA testing is not used as a standard test in men with LUTS, and patients are not referred to urologists at a sufficiently low PSA level to improve the early diagnosis and work-up of patients with suspected prostate cancer. However, the decision of many GPs to refer patients to urologists for further work-up is influenced by the findings of a DRE, the age of the patient and the PSA value itself. Further education regarding PSA testing amongst GPs in our area would seem to be appropriate.

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Year:  2005        PMID: 16118092     DOI: 10.1080/00365590510031084

Source DB:  PubMed          Journal:  Scand J Urol Nephrol        ISSN: 0036-5599


  9 in total

1.  The absence of voiding symptoms in men with a prostate-specific antigen (PSA) concentration of ≥3.0 ng/mL is an independent risk factor for prostate cancer: results from the Gothenburg Randomized Screening Trial.

Authors:  Maria Frånlund; Sigrid Carlsson; Johan Stranne; Gunnar Aus; Jonas Hugosson
Journal:  BJU Int       Date:  2012-04-30       Impact factor: 5.588

2.  Trends in prostate cancer survival in Spain: results from population-based cancer registries.

Authors:  Rafael Marcos-Gragera; Diego Salmerón; Isabel Izarzugaza; Eva Ardanaz; Bernat-Carles Serdà; Nerea Larrañaga; Erkuden San Román; Carmen Navarro; María-Dolores Chirlaque
Journal:  Clin Transl Oncol       Date:  2012-06       Impact factor: 3.405

3.  Fatherhood and incident prostate cancer in a prospective US cohort.

Authors:  Michael L Eisenberg; Yikyung Park; Louise A Brinton; Albert R Hollenbeck; Arthur Schatzkin
Journal:  Int J Epidemiol       Date:  2010-10-19       Impact factor: 7.196

4.  Algorithms, nomograms and the detection of indolent prostate cancer.

Authors:  Monique J Roobol
Journal:  World J Urol       Date:  2008-06-07       Impact factor: 4.226

5.  [Rates of prostate-specific antigen testing for early detection of prostate cancer: a first comparison of German results with current international data].

Authors:  S Lebentrau; M May; O Maurer; M Schostak; M Lehsnau; T Ecke; S Al-Dumaini; S Hallmann; A M Ahmed; V Braun; A Haferkamp; R M Bauer; C G Stief; D Baumunk; B Hoschke; H-P Braun; C Schäfer; M Hipp; J Maurer; K-P Braun; I Wolff; S Brookman-May; C Gilfrich
Journal:  Urologe A       Date:  2014-05       Impact factor: 0.639

Review 6.  Prostate specific antigen testing policy worldwide varies greatly and seems not to be in accordance with guidelines: a systematic review.

Authors:  Saskia Van der Meer; Sabine A M Löwik; Willem H Hirdes; Rien M Nijman; Klaas Van der Meer; Josette E H M Hoekstra-Weebers; Marco H Blanker
Journal:  BMC Fam Pract       Date:  2012-10-11       Impact factor: 2.497

7.  Survival of prostate cancer patients in central and northern Denmark, 1998-2009.

Authors:  Michael Borre; Rune Erichsen; Lars Lund; Erik Højkjær Larsen; Mette Nørgaard; Jacob Bonde Jacobsen
Journal:  Clin Epidemiol       Date:  2011-07-21       Impact factor: 4.790

8.  Danish General Practitioners' Use of Prostate-Specific Antigen in Opportunistic Screening for Prostate Cancer: A Survey Comprising 174 GPs.

Authors:  Kasper Jessen; Jens Søndergaard; Pia Veldt Larsen; Janus Laust Thomsen
Journal:  Int J Family Med       Date:  2013-11-19

9.  Attitudes Toward and Use of Prostate-Specific Antigen Testing Among Urologists and General Practitioners in Germany: A Survey.

Authors:  Sanny Kappen; Verena Jürgens; Michael H Freitag; Alexander Winter
Journal:  Front Oncol       Date:  2021-06-04       Impact factor: 6.244

  9 in total

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