Literature DB >> 16113780

Ultrasound thrombolysis.

Stefan Pfaffenberger1, Branka Devcic-Kuhar, Stefan P Kastl, Kurt Huber, Gerald Maurer, Johann Wojta, Michael Gottsauner-Wolf.   

Abstract

Cardiovascular diseases are a major cause of mortality in the developed world. Efficacy of thrombolysis plays an important role in the management of acute myocardial infarction and cerebral insult both in the acute event and in the long-term outcome of these patients. New adjunctive strategies have been tested, therefore, to make thrombolytic therapies more effective and safer. Ultrasound Thrombolysis is a technique which showed promising results under in vitro conditions and in animal studies. Now clinical trials have to prove if it is also feasible for clinical application. This report gives an overview on different technical approaches and their current performances in the clinical setting. All original articles are chronologically ordered in tables providing detailed information on each study concerning experimental design, acoustical parameters and thrombolysis outcome.

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Year:  2005        PMID: 16113780     DOI: 10.1160/TH04-12-0818

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN: 0340-6245            Impact factor:   5.249


  10 in total

1.  Ultrasound-induced thermal elevation in clotted blood and cranial bone.

Authors:  Volodymyr Nahirnyak; T Douglas Mast; Christy K Holland
Journal:  Ultrasound Med Biol       Date:  2007-05-09       Impact factor: 2.998

2.  In vitro and in vivo high-intensity focused ultrasound thrombolysis.

Authors:  Cameron Wright; Kullervo Hynynen; David Goertz
Journal:  Invest Radiol       Date:  2012-04       Impact factor: 6.016

3.  Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model.

Authors:  Adam D Maxwell; Gabe Owens; Hitinder S Gurm; Kimberly Ives; Daniel D Myers; Zhen Xu
Journal:  J Vasc Interv Radiol       Date:  2010-12-30       Impact factor: 3.464

4.  Pulsed focused ultrasound-induced displacements in confined in vitro blood clots.

Authors:  Cameron C Wright; Kullervo Hynynen; David E Goertz
Journal:  IEEE Trans Biomed Eng       Date:  2011-12-21       Impact factor: 4.538

5.  Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study.

Authors:  Michael J Stone; Victor Frenkel; Sergio Dromi; Peter Thomas; Ryan P Lewis; King C P Li; McDonald Horne; Bradford J Wood
Journal:  Thromb Res       Date:  2007-05-04       Impact factor: 3.944

6.  Effect of Thrombus Composition and Viscosity on Sonoreperfusion Efficacy in a Model of Micro-Vascular Obstruction.

Authors:  John J Black; Francois T H Yu; Rick G Schnatz; Xucai Chen; Flordeliza S Villanueva; John J Pacella
Journal:  Ultrasound Med Biol       Date:  2016-05-17       Impact factor: 2.998

Review 7.  Ultrasound mediated delivery of drugs and genes to solid tumors.

Authors:  Victor Frenkel
Journal:  Adv Drug Deliv Rev       Date:  2008-04-03       Impact factor: 15.470

8.  In vitro investigations into enhancement of tPA bioavailability in whole blood clots using pulsed-high intensity focused ultrasound exposures.

Authors:  Guy Jones; Finnie Hunter; Hilary A Hancock; Ankur Kapoor; Michael J Stone; Bradford J Wood; Jianwu Xie; Matthew R Dreher; Victor Frenkel
Journal:  IEEE Trans Biomed Eng       Date:  2010-01       Impact factor: 4.538

9.  In-vitro sonothrombolysis using thick-shelled polymer microbubbles - a comparison with thin-shelled microbubbles.

Authors:  Jovana Janjic; Malin K Larsson; Anna Bjällmark
Journal:  Cardiovasc Ultrasound       Date:  2020-05-04       Impact factor: 2.062

10.  Ultrasound enhanced prehospital thrombolysis using microbubbles infusion in patients with acute ST elevation myocardial infarction: rationale and design of the Sonolysis study.

Authors:  Jeroen Slikkerveer; Pieter A Dijkmans; Gertjan T Sieswerda; Pieter A F M Doevendans; Arie P J van Dijk; Freek W A Verheugt; Thomas R Porter; Otto Kamp
Journal:  Trials       Date:  2008-12-10       Impact factor: 2.279

  10 in total

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