Literature DB >> 16112860

An antitumor compound julibroside J28 from Albizia julibrissin.

Hong Liang1, Wen-yong Tong, Yu-ying Zhao, Jing-rong Cui, Guang-zhong Tu.   

Abstract

A new triterpenoid saponin, julibroside J(28) (1), was isolated from the stem bark of Albizia julibrissin Durazz (Leguminosae) by using chromatographic method. The structure of 1 was established by spectroscopic methods. 1 displayed significant antitumor activity in vitro against PC-3M-1E8, Bel-7402, and HeLa cancer cell lines at 10 microM assayed by SRB method.

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Year:  2005        PMID: 16112860     DOI: 10.1016/j.bmcl.2005.07.015

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  5 in total

1.  Cytotoxic triterpenoid saponins of Albizia gummifera from the Madagascar rain forest.

Authors:  Shugeng Cao; Andrew Norris; James S Miller; Fidy Ratovoson; Jeremi Razafitsalama; Rabodo Andriantsiferana; Vincent E Rasamison; Karen TenDyke; Ted Suh; David G I Kingston
Journal:  J Nat Prod       Date:  2007-01-31       Impact factor: 4.050

2.  Synthesis of a tetra- and a trisaccharide related to an anti-tumor saponin "Julibroside J28" from Albizia julibrissin.

Authors:  Bimalendu Roy; Kausikisankar Pramanik; Balaram Mukhopadhyay
Journal:  Glycoconj J       Date:  2007-08-16       Impact factor: 2.916

3.  Total saponins from Albizia julibrissin inhibit vascular endothelial growth factor-mediated angiogenesis in vitro and in vivo.

Authors:  Weiwei Cai; Yue Li; Qingqing Yi; Fengshan Xie; Bin Du; Lei Feng; Liying Qiu
Journal:  Mol Med Rep       Date:  2015-01-20       Impact factor: 2.952

4.  New acyclic secondary metabolites from the biologically active fraction of Albizia lebbeck flowers.

Authors:  Shaza M Al-Massarani; Ali A El Gamal; Mohamed F Abd El Halim; Mansour S Al-Said; Maged S Abdel-Kader; Omer A Basudan; Saleh I Alqasoumi
Journal:  Saudi Pharm J       Date:  2016-05-24       Impact factor: 4.330

5.  Albizia julibrissin Ameliorates Memory Loss Induced by Insomnia in Drosophila.

Authors:  Jui-Shu Chang; Hsin-Ping Liu; Jack Cheng; Chao-Jung Chen; Su-Lun Hwang; Chi-Chuan Tseng; Lee-Fen Hsu; Wei-Yong Lin
Journal:  Evid Based Complement Alternat Med       Date:  2019-04-01       Impact factor: 2.629

  5 in total

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