Literature DB >> 16111539

MLL-MLLT10 fusion gene in pediatric acute megakaryoblastic leukemia.

Cristina Morerio1, Annamaria Rapella, Elisa Tassano, Cristina Rosanda, Claudio Panarello.   

Abstract

The occurrence of MLL gene rearrangement in acute megakaryoblastic leukemia (AML-M7, acute myeloid leukemia, French-American-British type M7) is very rare and limited to pediatric age: in particular, MLL-MLLT10 fusion, previously reported as characteristic of monocytic leukemia, has been reported in only one case of pediatric megakaryoblastic leukemia. We describe the second case with this association in light of the few reported cases of AML-M7 with MLL and/or 11q23 involvement.

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Year:  2005        PMID： 16111539     DOI： 10.1016/j.leukres.2005.03.008

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  5 in total

1.  Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

Authors:  Jean-Pierre Bourquin; Aravind Subramanian; Claudia Langebrake; Dirk Reinhardt; Olivier Bernard; Paola Ballerini; André Baruchel; Hélène Cavé; Nicole Dastugue; Henrik Hasle; Gertjan L Kaspers; Michel Lessard; Lucienne Michaux; Paresh Vyas; Elisabeth van Wering; Christian M Zwaan; Todd R Golub; Stuart H Orkin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-21       Impact factor: 11.205

2.  miR-331-3p Inhibits Tumor Cell Proliferation, Metastasis, Invasion by Targeting MLLT10 in Non-Small Cell Lung Cancer.

Authors:  Qing-Qing Tian; Jing Xia; Xin Zhang; Bao-Qin Gao; Wei Wang
Journal:  Cancer Manag Res       Date:  2020-07-14       Impact factor: 3.989

Review 3.  The role of CALM-AF10 gene fusion in acute leukemia.

Authors:  D Caudell; P D Aplan
Journal:  Leukemia       Date:  2007-12-20       Impact factor: 11.528

4.  The Association of the Copy Number Variation of the MLLT10 Gene with Growth Traits of Chinese Cattle.

Authors:  Peng Yang; Zijing Zhang; Jiawei Xu; Kaixing Qu; Shijie Lyv; Xianwei Wang; Cuicui Cai; Zhiming Li; Eryao Wang; Jianliang Xie; Baorui Ru; Zejun Xu; Chuzhao Lei; Hong Chen; Bizhi Huang; Yongzhen Huang
Journal:  Animals (Basel)       Date:  2020-02-05       Impact factor: 2.752

5.  Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.

Authors:  Clarisse Thiollier; Cécile K Lopez; Bastien Gerby; Cathy Ignacimouttou; Sandrine Poglio; Yannis Duffourd; Justine Guégan; Paola Rivera-Munoz; Olivier Bluteau; Vinciane Mabialah; M'boyba Diop; Qiang Wen; Arnaud Petit; Anne-Laure Bauchet; Dirk Reinhardt; Beat Bornhauser; Daniel Gautheret; Yann Lecluse; Judith Landman-Parker; Isabelle Radford; William Vainchenker; Nicole Dastugue; Stéphane de Botton; Philippe Dessen; Jean-Pierre Bourquin; John D Crispino; Paola Ballerini; Olivier A Bernard; Françoise Pflumio; Thomas Mercher
Journal:  J Exp Med       Date:  2012-10-08       Impact factor: 14.307
  5 in total

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