Literature DB >> 16109083

Podocyte biology in human disease.

Janak Rashme de Zoysa1, Peter Stewart Topham.   

Abstract

The podocyte is a highly specialized cell that plays a key role in regulating the glomerular filtration barrier. A number of advances have been made in recent years, linked to the discovery of single-gene defects in hereditary glomerular disease, which highlight the role of this cell in preventing proteinuria. This article reviews the molecular biology of the podocyte, focusing on known genetic abnormalities.

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Year:  2005        PMID： 16109083     DOI： 10.1111/j.1440-1797.2005.00401.x

Source DB:  PubMed          Journal:  Nephrology (Carlton)        ISSN： 1320-5358            Impact factor:   2.506


  5 in total

1.  Familial steroid-sensitive nephrotic syndrome in Southern Israel: clinical and genetic observations.

Authors:  Daniel Landau; Tal Oved; Dan Geiger; Luba Abizov; Hanna Shalev; Ruti Parvari
Journal:  Pediatr Nephrol       Date:  2007-01-12       Impact factor: 3.714

2.  The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development.

Authors:  Paul T Kroeger; Bridgette E Drummond; Rachel Miceli; Michael McKernan; Gary F Gerlach; Amanda N Marra; Annemarie Fox; Kristen K McCampbell; Ignaty Leshchiner; Adriana Rodriguez-Mari; Ruth BreMiller; Ryan Thummel; Alan J Davidson; John Postlethwait; Wolfram Goessling; Rebecca A Wingert
Journal:  Dev Biol       Date:  2017-06-01       Impact factor: 3.582

3.  Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan.

Authors:  Yu-Huei Liu; Cheng-Hsu Chen; Shih-Yin Chen; Ying-Ju Lin; Wen-Ling Liao; Chang-Hai Tsai; Lei Wan; Fuu-Jen Tsai
Journal:  J Biomed Sci       Date:  2010-10-11       Impact factor: 8.410

4.  Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia.

Authors:  Shuang Zhao; Xin Gu; Lynn J Groome; Yuping Wang
Journal:  Reprod Sci       Date:  2009-06-15       Impact factor: 3.060

Review 5.  A compendium of urinary biomarkers indicative of glomerular podocytopathy.

Authors:  Miroslav Sekulic; Simona Pichler Sekulic
Journal:  Patholog Res Int       Date:  2013-11-13
  5 in total

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