| Literature DB >> 16087400 |
Timo K van den Berg1, Georg Kraal.
Abstract
The F4/80 monoclonal antibody has been used widely as a marker for mouse macrophages. The antigen (Ag) recognized by the antibody has been characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family, although the function of the molecule has remained elusive. A recent study provides evidence for a role of the F4/80 molecule in the induction of immunological tolerance. This study appears to provide clear evidence for a role of the F4/80 molecule in the immune system, however, what does it really tell us about the activities of the F4/80 molecule?Entities:
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Year: 2005 PMID： 16087400 DOI： 10.1016/j.it.2005.07.008
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687