Literature DB >> 16085898

Genetic analysis of two bile salt hydrolase activities in Lactobacillus acidophilus NCFM.

Olivia McAuliffe1, Raul J Cano, Todd R Klaenhammer.   

Abstract

Two genes, bshA and bshB, encoding bile salt hydrolase enzymes (EC 3.5.1.24) were identified in the genome sequence of Lactobacillus acidophilus NCFM. Targeted inactivation of these genes via chromosomal insertion of an integration vector demonstrated different substrate specificities for these two enzymes.

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Year:  2005        PMID： 16085898      PMCID： PMC1183333          DOI： 10.1128/AEM.71.8.4925-4929.2005

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  30 in total

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Journal:  Science       Date:  2003-03-28       Impact factor: 47.728

2.  Multiple forms of bile salt hydrolase from Lactobacillus sp. strain 100-100.

Authors:  S G Lundeen; D C Savage
Journal:  J Bacteriol       Date:  1992-11       Impact factor: 3.490

3.  GAMOLA: a new local solution for sequence annotation and analyzing draft and finished prokaryotic genomes.

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Authors: 
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8.  Cloning and characterization of the bile salt hydrolase genes (bsh) from Bifidobacterium bifidum strains.

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9.  16S ribosomal DNA analysis of the faecal lactobacilli composition of human subjects consuming a probiotic strain Lactobacillus acidophilus NCFM.

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2.  Characterization of a novel bile-inducible operon encoding a two-component regulatory system in Lactobacillus acidophilus.

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Review 3.  Bile salt hydrolase activity in probiotics.

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Journal:  Appl Environ Microbiol       Date:  2006-03       Impact factor: 4.792

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5.  Screening, Characterization and In Vitro Evaluation of Probiotic Properties Among Lactic Acid Bacteria Through Comparative Analysis.

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Review 6.  Bile salt hydrolases: Structure and function, substrate preference, and inhibitor development.

Authors:  Zixing Dong; Byong H Lee
Journal:  Protein Sci       Date:  2018-09-24       Impact factor: 6.725

7.  Relative gene expression of bile salt hydrolase and surface proteins in two putative indigenous Lactobacillus plantarum strains under in vitro gut conditions.

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8.  Identification of proteins related to the stress response in Enterococcus faecalis V583 caused by bovine bile.

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9.  Molecular cloning, characterization and heterologous expression of bile salt hydrolase (Bsh) from Lactobacillus fermentum NCDO394.

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10.  Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism.

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Journal:  Appl Environ Microbiol       Date:  2008-06-06       Impact factor: 4.792
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