Literature DB >> 16077168

Immunohistological study for estrogenic activities of nitrophenols in diesel exhaust particles.

Chie Furuta1, ChunMei Li, Shinji Taneda, Akira K Suzuki, Kazuyuki Kamata, Gen Watanabe, Kazuyoshi Taya.   

Abstract

We recently isolated 3-methyl-4-nitrophenol (4-nitro-m-cresol; PNMC) and 4-nitro-3-phenylphenol (PNMPP) from diesel exhaust particles (DEP) and identified them as vasodilators and xenoestrogens. The estrogenic activity of PNMC and PNMPP was further examined by using immunohistochemical staining of proliferating cell nuclear antigen (PCNA) in uterine luminal epithelium of ovariectomized 25-d-old immature female rats injected with PNMC and PNMPP subcutaneously for 2 d. Significant increases were observed in uterine luminal epithelium in PCNA positive cells of animals receiving 10 and 100 mg/kg PNMC and 0.1 mg/kg PNMPP compared with controls. These results clearly show the estrogenic activity of PNMC and PNMPP by cell proliferation on the uterine luminal epithelium.

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Year:  2005        PMID： 16077168     DOI： 10.1385/ENDO:27:1:033

Source DB:  PubMed          Journal:  Endocrine        ISSN： 1355-008X            Impact factor:   3.633


  21 in total

1.  Diesel-exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice.

Authors:  S Takafuji; S Suzuki; K Koizumi; K Tadokoro; T Miyamoto; R Ikemori; M Muranaka
Journal:  J Allergy Clin Immunol       Date:  1987-04       Impact factor: 10.793

2.  Adjuvant activity of diesel-exhaust particulates for the production of IgE antibody in mice.

Authors:  M Muranaka; S Suzuki; K Koizumi; S Takafuji; T Miyamoto; R Ikemori; H Tokiwa
Journal:  J Allergy Clin Immunol       Date:  1986-04       Impact factor: 10.793

3.  Different residues of the human estrogen receptor are involved in the recognition of structurally diverse estrogens and antiestrogens.

Authors:  K Ekena; K E Weis; J A Katzenellenbogen; B S Katzenellenbogen
Journal:  J Biol Chem       Date:  1997-02-21       Impact factor: 5.157

4.  Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles.

Authors:  T Ichinose; Y Yajima; M Nagashima; S Takenoshita; Y Nagamachi; M Sagai
Journal:  Carcinogenesis       Date:  1997-01       Impact factor: 4.944

5.  Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding.

Authors:  K Ekena; K E Weis; J A Katzenellenbogen; B S Katzenellenbogen
Journal:  J Biol Chem       Date:  1996-08-16       Impact factor: 5.157

6.  The environmental estrogen bisphenol A stimulates prolactin release in vitro and in vivo.

Authors:  R Steinmetz; N G Brown; D L Allen; R M Bigsby; N Ben-Jonathan
Journal:  Endocrinology       Date:  1997-05       Impact factor: 4.736

7.  PC10 monoclonal antibody to proliferating cell nuclear antigen as probe for cycling cell detection in developing tissues. A combined immunocytochemical and flow cytometric study.

Authors:  A Casasco; M Giordano; M Danova; M Casasco; A Icaro Cornaglia; A Calligaro
Journal:  Histochemistry       Date:  1993-03

8.  [Expression of proliferating cell nuclear antigen in superficial bladder cancer--application to paraffin-embedded tissue sections].

Authors:  T Wada; T Shimabukuro; H Kurisu; I A Shameem; S Yoshihiro; H Matsuyama; K Naito; O Hashimoto; K Tanaka
Journal:  Hinyokika Kiyo       Date:  1993-04

9.  Diesel exhaust inhalation enhances airway hyperresponsiveness in mice.

Authors:  Y Miyabara; T Ichinose; H Takano; M Sagai
Journal:  Int Arch Allergy Immunol       Date:  1998-06       Impact factor: 2.749

Review 10.  Health effects of exposure to diesel exhaust particles.

Authors:  R O McClellan
Journal:  Annu Rev Pharmacol Toxicol       Date:  1987       Impact factor: 13.820
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  7 in total

1.  Alleviative effect of quercetin on germ cells intoxicated by 3-methyl-4-nitrophenol from diesel exhaust particles.

Authors:  Tong-liang Bu; Yu-dong Jia; Jin-xing Lin; Yu-ling Mi; Cai-qiao Zhang
Journal:  J Zhejiang Univ Sci B       Date:  2012-04       Impact factor: 3.066

2.  In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice.

Authors:  Tomoharu Suzuki; Shigeru Oshio; Mari Iwata; Hisayo Saburi; Takashi Odagiri; Tadashi Udagawa; Isamu Sugawara; Masakazu Umezawa; Ken Takeda
Journal:  Part Fibre Toxicol       Date:  2010-03-23       Impact factor: 9.400

3.  4-Nitrophenol isolated from diesel exhaust particles disrupts regulation of reproductive hormones in immature male rats.

Authors:  Xuezheng Li; Chunmei Li; Akira K Suzuki; Shinji Taneda; Gen Watanabe; Kazuyoshi Taya
Journal:  Endocrine       Date:  2009-04-29       Impact factor: 3.633

4.  Improvement of an efficient separation method for chemicals in diesel exhaust particles: analysis for nitrophenols.

Authors:  Yoichi Noya; Yusuke Mikami; Shinji Taneda; Yoki Mori; Akira K Suzuki; Kazue Ohkura; Kouya Yamaki; Shin Yoshino; Koh-ichi Seki
Journal:  Environ Sci Pollut Res Int       Date:  2008-04-24       Impact factor: 4.223

5.  4-Nitro-3-phenylphenol has both androgenic and anti-androgenic-like effects in rats.

Authors:  Jiratthiya Trisomboon; ChunMei Li; Akira Suzuki; Gen Watanabe; Kazuyoshi Taya
Journal:  J Reprod Dev       Date:  2015-01-15       Impact factor: 2.214

6.  Suppressive effects of long-term exposure to P-nitrophenol on gonadal development, hormonal profile with disruption of tissue integrity, and activation of caspase-3 in male Japanese quail (Coturnix japonica).

Authors:  Eman Ahmed; Kentaro Nagaoka; Mostafa Fayez; Mohamed M Abdel-Daim; Haney Samir; Gen Watanabe
Journal:  Environ Sci Pollut Res Int       Date:  2015-03-15       Impact factor: 4.223

7.  Walnut Polyphenol Extract Attenuates Immunotoxicity Induced by 4-Pentylphenol and 3-methyl-4-nitrophenol in Murine Splenic Lymphocyte.

Authors:  Lubing Yang; Sihui Ma; Yu Han; Yuhan Wang; Yan Guo; Qiang Weng; Meiyu Xu
Journal:  Nutrients       Date:  2016-05-12       Impact factor: 5.717
  7 in total

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