Literature DB >> 16076978

A pilot study of the quality of informed consent materials for Aboriginal participants in clinical trials.

F M Russell1, J R Carapetis, H Liddle, T Edwards, T A Ruff, J Devitt.   

Abstract

OBJECTIVE: To pilot informed consent materials developed for Aboriginal parents in a vaccine trial, and evaluate their design and the informed consent process.
METHODS: Cross sectional quantitative and qualitative survey of 20 Aboriginal and 20 non-Aboriginal women in Alice Springs. Information about the proposed research was presented to Aboriginal participants by an Aboriginal researcher, using purpose designed verbal, visual, and written materials. Non-Aboriginal participants received standard materials developed by the sponsor. Questionnaires were used to evaluate recall and understanding immediately and five days later. Qualitative analysis of Aboriginal participants' interviews was performed.
RESULTS: There were no differences between the groups in understanding of diseases prevented by the vaccine, the potential risks of participating, or the voluntary nature of participation. Most Aboriginal participants had difficulty with the concept of a "licensed" versus "unlicensed" vaccine. The non-Aboriginal group had a good understanding of this. Aboriginal participants identified the use of the flipchart, along with a presentation by a doctor and Aboriginal health worker, as preferred delivery modes. Group presentations were preferred rather than one-on-one discussions. The use of the questionnaire posed considerable methodological difficulties.
CONCLUSIONS: A one-off oral presentation to Aboriginal participants is unlikely to produce "informed consent". Key but unfamiliar concepts require identification and particularly considered presentation.

Entities:  

Keywords:  Biomedical and Behavioral Research; Empirical Approach

Mesh:

Substances:

Year:  2005        PMID: 16076978      PMCID: PMC1734200          DOI: 10.1136/jme.2002.002279

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  8 in total

1.  Usable written information for patients.

Authors:  D Sless
Journal:  Med J Aust       Date:  2001-06-04       Impact factor: 7.738

2.  Discourse analysis: a new methodology for understanding the ideologies of health and illness.

Authors:  D Lupton
Journal:  Aust J Public Health       Date:  1992-06

3.  The ethics of informed consent among storyteller cultures.

Authors:  J K Casteel
Journal:  Int J Circumpolar Health       Date:  1998       Impact factor: 1.228

4.  Questionnaire design.

Authors:  L Fallowfield
Journal:  Arch Dis Child       Date:  1995-01       Impact factor: 3.791

5.  Evolving participation of aboriginal communities in health research ethics review: the impact of the Inuvik workshop.

Authors:  J Kaufert; L Commanda; B Elias; R Grey; T KueYoung; B Masuzumi
Journal:  Int J Circumpolar Health       Date:  1999-04       Impact factor: 1.228

6.  Readability and content of supplementary written drug information for patients used by Australian rheumatologists.

Authors:  R Buchbinder; S Hall; G Grant; A Mylvaganam; M R Patrick
Journal:  Med J Aust       Date:  2001-06-04       Impact factor: 7.738

7.  Readability of pediatric biomedical research informed consent forms.

Authors:  K J Tarnowski; D M Allen; C Mayhall; P A Kelly
Journal:  Pediatrics       Date:  1990-01       Impact factor: 7.124

Review 8.  Informed consent for clinical trials: in search of the "best" method.

Authors:  S J Edwards; R J Lilford; J Thornton; J Hewison
Journal:  Soc Sci Med       Date:  1998-12       Impact factor: 4.634

  8 in total
  7 in total

Review 1.  Seeking consent for research with indigenous communities: a systematic review.

Authors:  Emily F M Fitzpatrick; Alexandra L C Martiniuk; Heather D'Antoine; June Oscar; Maureen Carter; Elizabeth J Elliott
Journal:  BMC Med Ethics       Date:  2016-10-22       Impact factor: 2.652

2.  Conceptual framework for behavioral and social science in HIV vaccine clinical research.

Authors:  Chuen-Yen Lau; Edith M Swann; Sagri Singh; Zuhayr Kafaar; Helen I Meissner; James P Stansbury
Journal:  Vaccine       Date:  2011-08-05       Impact factor: 3.641

3.  Reflexive research ethics in fetal tissue xenotransplantation research.

Authors:  Bindu Panikkar; Natasha Smith; Phil Brown
Journal:  Account Res       Date:  2012       Impact factor: 2.622

Review 4.  Participants' understanding of informed consent in clinical trials over three decades: systematic review and meta-analysis.

Authors:  Nguyen Thanh Tam; Nguyen Tien Huy; Le Thi Bich Thoa; Nguyen Phuoc Long; Nguyen Thi Huyen Trang; Kenji Hirayama; Juntra Karbwang
Journal:  Bull World Health Organ       Date:  2015-01-22       Impact factor: 9.408

5.  The Picture Talk Project: Starting a Conversation with Community Leaders on Research with Remote Aboriginal Communities of Australia.

Authors:  E F M Fitzpatrick; G Macdonald; A L C Martiniuk; H D'Antoine; J Oscar; M Carter; T Lawford; E J Elliott
Journal:  BMC Med Ethics       Date:  2017-05-11       Impact factor: 2.652

6.  The picture talk project: Aboriginal community input on consent for research.

Authors:  Emily Fm Fitzpatrick; Gaynor Macdonald; Alexandra Lc Martiniuk; June Oscar; Heather D'Antoine; Maureen Carter; Tom Lawford; Elizabeth J Elliott
Journal:  BMC Med Ethics       Date:  2019-01-29       Impact factor: 2.652

7.  Health research policy: a case study of policy change in Aboriginal and Torres Strait Islander health research.

Authors:  Sophia Leon de la Barra; Sally Redman; Sandra Eades
Journal:  Aust New Zealand Health Policy       Date:  2009-02-26
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.