Differential susceptibility of the axilla and groin of the mouse to chemical oncogenesis.

INCIDENTAL to investigations of chemical oncogenesis, we have observed that 3-methylcholanthrene (3-MC)-induced subcutaneous sarcogenesis occurred more rapidly in the axillary than in the inguinal region of the mouse. Recently Auerbach et al. have described what may be a similar phenomenon-a marked tendency for tumour transplants to grow better cephalically(1,2).