Literature DB >> 16065066

The phosphoinositide-3-OH-kinase-related kinases of Arabidopsis thaliana.

George W Templeton1, Greg B G Moorhead.   

Abstract

The phosphoinositide-3-OH-kinase-related kinases (PIKKs) are atypical protein kinases exclusive to eukaryotes. They mediate the cellular response to a range of stresses, including genome and RNA surveillance and availability of nutrients for growth. Orthologues of five out of the six PIKK family members are present in plant genomes. Recent studies in plant PIKKs have revealed features unique to, and in common with, other PIKKs. This review summarizes the basic knowledge of these proteins in mammals and yeast in comparison with what is known for Arabidopsis and other plants.

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Year:  2005        PMID: 16065066      PMCID: PMC1369146          DOI: 10.1038/sj.embor.7400479

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


  32 in total

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